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Featured Products
Axon 1585
CAS [548472-68-0]
MF C30H30Cl2N4O4MW 581.49
MDM2 antagonist, which binds MDM2 in the p53-binding pocket and activates the p53 pathway in cancer cells, leading to cell cycle arrest, apoptosis, and growth inhibition of human tumor xenografts in nude mice.
Note: Its two enantiomers, more active (-)-enantiomer Nutlin-3a (Axon 1880) and less active (+)-enantiomer Nutlin-3b (Axon 1881), are also available.
4-(4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one
[548472-68-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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