Deguelin

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1239

CAS [522-17-8]

MF C23H22O6
MW 394.42

Purity: 98%
Soluble in DMSO and Ethanol

Deguelin

Description

Inhibitor of activated Akt. Anticancer, chemopreventive agent

AS Nair et al. Deguelin, an Akt Inhibitor, Suppresses IKBa Kinase Activation Leading to Suppression of NF-KB-Regulated Gene Expression, Potentiation of Apoptosis, and Inhibition of Cellular Invasion. J. Immunol. 2006, 177, 5612-5622.

KH Chun et al. Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. J. Natl. Cancer Inst. 2003, 95, 291-302.

Apoptosis Cell Signaling & Oncology Akt PI3K-Akt-mTOR EC 2.7.11.1

Akt inhibitor

Chemical name

(7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H,7aH-pyrano[2,3-c;6,5-f']dichromen-7-one

Parent CAS No.

[522-17-8]

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10 mg	$148.50	In Stock

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Deguelin

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Chemical name

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