Hesperadin

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2096

CAS [422513-13-1]

MF C29H32N4O3S
MW 516.65

Purity: 99%
Soluble in DMSO

Hesperadin

Description

A rapid, reversible and ATP-competitive inhibitor of Aurora B

S Hauf et al. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint. J. Cell Biol. 2003, 16192), 281.

F Sessa et al. Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Mol. Cell, 2005, 18(3), 379.

Cell Cycle Regulation Cell Signaling & Oncology Epigenetics EC 2.7.11.1 Aurora

Reversible and ATP-competitive inhibitor of Aurora B

Chemical name

(Z)-N-(2-oxo-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)methylene)indolin-5-yl)ethanesulfonamide

Parent CAS No.

[422513-13-1]

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5 mg	$104.50	In Stock
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Hesperadin

Description

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