VX 745

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1811

CAS [209410-46-8]

MF C19H9Cl2F2N3OS
MW 436.26

Purity: 99%
Soluble in DMSO

VX 745

Description

Highly potent and selective inhibitor of p38α MAP kinase (IC50: 10 nM); being 1000 fold selective over closely related kinases

JP Duffy et al. The discovery of VX-745: a novel and selective p38α kinase inhibitor. ACS Med. Chem. Lett. 2011, 2, 758.

MC Bagley et al. Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells. Bioorg. Med. Chem. Lett. 2007, 17(8), 5107-5110.

JJ Haddad. VX-745. Vertex Pharmaceuticals. Curr. Opin. Investig. Drugs. 2001, 2(8), 1070-1076.

Cell Signaling & Oncology MAPK (p38) MAPK EC 2.7.11.24

Inhibitor of p38α MAP kinase

Chemical name

5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one

Parent CAS No.

[209410-46-8]

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5 mg	$99.00	In Stock
25 mg	$363.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	$154.00	In Stock
2 x 25 mg	$528.00	In Stock

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成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

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VX 745

Description

Chemical name

Parent CAS No.

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