98% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

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UNC0379

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2418

CAS [1620401-82-2]

MF C23H35N5O2
MW 413.56

  • Purity: 98%
  • Soluble in DMSO

UNC0379

Description

Substrate competitive inhibitor of the H4K20 HMTase SETD8 (IC50 value 7.3 μM) with selectivity over 15 other methyltransferases including G9a and GLP. MOA studies revealed that UNC0379 is noncompetitive with the cofactor S-adenosyl-Lmethionine (SAM).
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50 mg $495.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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