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Featured Products
Axon 3000
CAS [1446817-84-0]
MF C20H22F9N3O2MW 507.39
ABX-1431 is a highly potent, selective, and orally available, CNS-penetrant MGLL (MAGL) inhibitor with an IC50 value of 0.014 µM. In vivo, ABX-1431 inhibits MGLL activity in rodent brain (ED50 value of 0.5-1.4 mg/kg), increases brain 2-AG concentrations, and suppresses pain behavior in the rat formalin pain model.
KEYWORDS: ABX-1431 | Supplier | MAGL inhibitor | ABX1431 | ABX 1431 | CAS [1446817-84-0] | 2-arachidonoyl glycerol (2-AG) | MAGL | Inhibitor | Enzymes | MGLL
1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate
[1446817-84-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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