P 22077

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1906

CAS [1247819-59-5]

MF C12H7F2NO3S2
MW 315.32

Purity: 99%
Soluble in DMSO

P 22077

Description

Small molecule inhibitor of deubiquitinase (DUB), specific on ubiquitin-specific protease 7 (USP7) and the closely related USP47; Inhibits USP7-mediated p53 deubiquitination

M Altun et al. Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes. Chem. Biol. 2011, 18, 1401–1412.

X Tian et al. Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format. Assay Drug Dev. Technol. 2011, 9(2), 165-173.

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Ubiquitin EC 3.4.19.12 Deubiquitinase

Inhibitor of deubiquitinase USP7 and USP47

Chemical name

1-(5-(2,4-difluorophenylthio)-4-nitrothiophen-2-yl)ethanone

Parent CAS No.

[1247819-59-5]

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10 mg	$104.50	In Stock
50 mg	$324.50	In Stock

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2 x 50 mg	$462.00	In Stock

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P 22077

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P 22077

Description

Chemical name

Parent CAS No.

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