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Axon 2464
CAS [1082949-68-5]
MF C21H19F4N7.C7H8O3SMW 617.62
Oral, selective ATP-competitive inhibitor of p70 S6 kinase (S6K1; IC50 value 4 nM) with significant synergistic activity with Erlotinib (Axon 1128) and Everolimus (Axon 4149). LY2584702 is selective against 83 other kinases as determined by a ubiquitin kinase panel, and 45 cell surface markers as determined by a CEREP mini panel.
KEYWORDS: LY 2584702 tosylate | supplier | S6K1 inhibitor | LY 2779964 | LY2584702 | LY2779964 | CAS [1082949-68-5] | [1082949-67-4] | (Ribosomal proteins) | p70-RSK | Inhibitor | p70S6K | PI3K | mTOR | Akt | ribosomal | cancer | Phase I | trial | ATP-competitive
4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine tosylate
[1082949-67-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2021 Spring Edition
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