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Axon 2883
CAS [100750-39-8]
MF C14H13NO3MW 243.26
APPA is an aldose reductase inhibitor with an IC50 value of 0.0223 μM. APPA could inhibit apoptosis in rat glomerular mesangial cells in vitro. In addition, APPA improved the pathological symptoms of streptozotocin-induced diabetic nephropathy (DN) in rats by affecting antioxidant activities and reducing the levels of TGF-β, collagen IV, and laminin.
KEYWORDS: APPA | supplier | Aldose reductase inhibitor | CAS [100750-39-8] | Aldose | Aldose reductase | Inhibitor | Enzymes | Diabetic Nephropathy | Diabetes Mellitus | Polyol Pathway
1-Acetyl-5-phenyl-1H-pyrrol-3-yl acetate
[100750-39-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue 2025 Spring Edition
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