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In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Tandospirone (SM-3997; sediel ) is an anxiolytic and antidepressant [1].
Tandospirone has been reported to produce a significant increase in number of shocks at doses of 5 and 10mg/kg, i .p. or 20 and 40 mg/kg, p.o.. 10mg/kg, i.p. of Tandospirone has been revealed to produce a significant increase in the number of shocks following the repeated treatment for 5 or 10 days. In addition, has been noted to impair rota-rod performance at relatively high doses with ED50 values of 207 mg/kg, p.o. and 300mg/kg, p.o. in mice and rats, respectively. Besides, Tandospirone has been evaluated to enhance the duration of the hexobarbital-induced anesthesia with an ED50 value of 212mg/kg, p.o. [1].
References:[1] Shimizu H1, Hirose A, Tatsuno T, Nakamura M, Katsube J. Pharmacological properties of SM-3997: a new anxioselective anxiolytic candidate. Jpn J Pharmacol. 1987 Dec; 45(4):493-500.
