Afatinib dimaleate

Catalog No.

A3145

EGFR inhibitor

Grouped product items
Size	Price	Stock
10mM (in 1mL DMSO)	$66.00	In stock
5mg	$55.00	In stock
10mg	$77.00	In stock
50mg	$121.00	In stock

For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Background

Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	718.08
Cas No.	850140-73-7
Formula	C₃₂H₃₃ClFN₅O₁₁
Synonyms	BIBW 2992MA2; BIBW-2992; BIBW2992; BIBW 2992; Afatinib
Solubility	≥35.9 mg/mL in DMSO; ≥147.2 mg/mL in H2O; ≥6.39 mg/mL in EtOH with gentle warming and ultrasonic
Chemical Name	(Z)-but-2-enedioic acid;(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
SDF	Download SDF
Canonical SMILES	CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Purity = 98.28%