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Avermectin B1

Catalog No.
A3202
Insecticide
Grouped product items
SizePriceStock Qty
100mg
$59.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. Avermectin B1 is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b. These two components, B1a and B1b have very similar biological and toxicological properties. The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium Streptomyces avermitilis. Avermectin B1 is a natural fermentation product of this bacterium.

Chemical Properties

Physical AppearanceA crystalline solid
StorageStore at -20°C
M.Wt873.08
Cas No.71751-41-2
FormulaC48H72O14
SynonymsAbamectin; Avermectin B1a-Avermectin B1b mixt.
SolubilitySoluble in DMSO
SDFDownload SDF
Canonical SMILESCCC(C1C(C)C=CC2(CC3CC(C/C=C(C)/C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)/C=C/C=C6COC7C\6(O)C(C(O3)=O)C=C(C)C7O)O2)O1)C
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Protocol

Animal experiment [1]:

Animal models

Horses and ponies

Dosage form

0.2 mg/kg (p.o.)

Application

Avermectin B1 treatment resulted in a significant decrease in the average number of strongyle egg counts the 14, 28 and 42 days. Oral administration of this avermectin B1 formulation appeared to be very effective against the intestinal strongyles and Onchocera microfilaria. However, the duration of anti- strongyle activity was much shorter than that of ivermectin paste.

Other notes

Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.

References:

[1]. Mogg TD, Pollitt CC, Willmore JP, Thompson H. Efficacy of avermectin B1 given orally against equine intestinal strongyles and Onchocera microfilaria. Aust Vet J. 1990 Nov;67(11):399-401. doi: 10.1111/j.1751-0813.1990.tb03026.x. PMID: 2085293.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Avermectin B1