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- Praziquantel
Praziquantel
| Storage | Store at -20°C |
| M.Wt | 312.41 |
| Cas No. | 55268-74-1 |
| Formula | C19H24N2O2 |
| Solubility | insoluble in H2O; ≥14.35 mg/mL in DMSO; ≥30.35 mg/mL in EtOH |
| Chemical Name | 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one |
| SDF | Download SDF |
| Canonical SMILES | C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| Animal experiment [1]: | |
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Animal models |
Female albino mice infected by S. mansoni |
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Dosage form |
200 mg/kg, oral gavage |
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Application |
Praziquantel selection resulted in a striking increase in the number of recovered parasites after treatment with this drug, compared with the number recovered after equivalent treatment of non-selected parasites. |
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Other notes |
Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal. |
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References: [1]. Coeli R, Baba EH, Araujo N, Coelho PM, Oliveira G. Praziquantel treatment decreases Schistosoma mansoni genetic diversity in experimental infections. PLoS Negl Trop Dis. 2013 Dec 19;7(12): e2596. doi: 10.1371/journal.pntd.0002596. eCollection 2013. PubMed PMID: 24367712; PubMed Central PMCID: PMC3868512. |
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Quality Control & MSDS
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Chemical structure
