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In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Cell lines
Atopobium vaginae, G. vaginalis, Lactobacillus
Preparation method
The solubility of this compound in DMSO is soluble. General tips for obtaining a higher concentration: Please warm the tube at 37 ℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.
Reacting condition
0.125 μg/ml-0.5 μg/ml
Applications
In vitro, nifuratel is able to inhibit the growth of Atopobium vaginae with a MIC range of 0.125-1 μg / mL. It is active against G.vaginalis and does not affect lactobacillus. These observations suggested that nifuratel may be the most effective treatment for bacterial vaginosis.
References:
[1]. Polatti F. Bacterial vaginosis, Atopobium vaginae and nifuratel. Curr Clin Pharmacol. 2012 Feb 1;7(1):36-40. doi: 10.2174/157488412799218824. PMID: 22082330; PMCID: PMC3362959.