Edoxaban
Catalog No.
A3381
Factor Xa inhibitor
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Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention in patients with atrial fibrillation, an elderly population that frequently receives aspirin (ASA) and/or nonsteroidal anti-inflammatory drugs for concurrent illnesses.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 548.06 |
| Cas No. | 480449-70-5 |
| Formula | C24H30ClN7O4S |
| Synonyms | DU-176 |
| Solubility | ≥27.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| Chemical Name | N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide |
| SDF | Download SDF |
| Canonical SMILES | CN1CCC2=C(C1)SC(=N2)C(=O)NC3CC(CCC3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| Description | Edoxaban is a novel inhibitor of factor Xa with Ki value of 0.56 nM. | |||||
| Targets | factor Xa | |||||
| IC50 | 0.56 nM (Ki) | |||||
Quality Control & MSDS
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Chemical structure
