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Betulinic acid
Catalog No.
A3237
Anti-HIV and antitumor compound,pentacyclic triterpenoid
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Betulinic acid is a natural pentacyclic triterpenoid that displays anti-HIV and antitumor activity. Betulinic acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic acid also displays TGR5 agonist activity (EC50 =1.04 μM).
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 456.7 |
| Cas No. | 472-15-1 |
| Formula | C30H48O3 |
| Synonyms | Lupatic acid,Betulic acid,Mairin,NSC113090,NSC-113090 |
| Solubility | ≥22.85 mg/mL in DMSO; insoluble in H2O; ≥9.62 mg/mL in EtOH with gentle warming and ultrasonic |
| Chemical Name | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid |
| SDF | Download SDF |
| Canonical SMILES | [H][C@]12[C@@](CC[C@H]2C(C)=C)(C(O)=O)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@@]31[H] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
