成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

<noscript id="xyjh0"><legend id="xyjh0"><rp id="xyjh0"></rp></legend></noscript>

<source id="xyjh0"><bdo id="xyjh0"></bdo></source>

require.config({ deps: [ 'jquery', 'mage/translate', 'jquery/jquery-storageapi' ], callback: function ($) { 'use strict'; var dependencies = [], versionObj; $.initNamespaceStorage('mage-translation-storage'); $.initNamespaceStorage('mage-translation-file-version'); versionObj = $.localStorage.get('mage-translation-file-version'); if (versionObj.version !== '2945a803802eff1885867c4f1ead83ea9223774a') { dependencies.push( 'text!js-translation.json' ); } require.config({ deps: dependencies, callback: function (string) { if (typeof string === 'string') { $.mage.translate.add(JSON.parse(string)); $.localStorage.set('mage-translation-storage', string); $.localStorage.set( 'mage-translation-file-version', { version: '2945a803802eff1885867c4f1ead83ea9223774a' } ); } else { $.mage.translate.add($.localStorage.get('mage-translation-storage')); } } }); } }); { "*": { "mage/cookies": { "expires": null, "path": "/", "domain": ".www.apexbt.com", "secure": false, "lifetime": "3600" } } }<div id="ykaok2ay" class="message global noscript"><div id="ykaok2ay" class="content"><p><strong>JavaScript seems to be disabled in your browser.</strong> <span>For the best experience on our site, be sure to turn on Javascript in your browser.</span></p></div></div>

Home
5-hydroxypyrazine-2-carboxylic acid

Home
Signaling Pathways
Microbiology & Virology
Antibiotic
5-hydroxypyrazine-2-carboxylic acid

Home
Lab Reagents
Antibiotics
5-hydroxypyrazine-2-carboxylic acid

5-hydroxypyrazine-2-carboxylic acid

Catalog No.

A3124

Metabolite of pyrazinamide (PZA)

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
Size	Price	Stock	Qty
1g	$90.00	In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background
Chemical Properties
Protocol
Quality Control

Background

5-hydroxypyrazine-2-carboxylic acid , a metabolite of anti-tuberculosis drug pyrazinamide (PZA).

Chemical Properties

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	140.1
Cas No.	34604-60-9
Formula	C₅H₄N₂O₃
Solubility	insoluble in EtOH; ≥7 mg/mL in DMSO; ≥7.63 mg/mL in H2O
Chemical Name	5-hydroxypyrazine-2-carboxylic acid
SDF	Download SDF
Canonical SMILES	OC1=NC=C(C(O)=O)N=C1
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Protocol

Animal experiment [1]:
Animal models	Sprague-Dawley female rats
Dosage form	50mg/kg,100mg/kg(p.o.)
Application	Quantitative analysis of PZA and its three major metabolites in 24-hour urine samples were performed by reversed-phase high-performance liquid chromatography. Caffeine (100mg/kg) and PZA (50mg/kg) administered simultaneously increase the excretion of the most soluble and least toxic PZA metabolite 5-hydroxypyrazine-2-carboxylic acid (from 66.18 +/- 10.87 to 94.56 + /-8.65μM / 24 h). This effect was even more pronounced when PZA was administered at 100 mg / kg: the excretion of 5-OH-PA was increased from 113.28 +/- 70 to 173.23 +/- 17.82 μM / 24 h. These results suggest that caffeine intake can affect PZA metabolism.
Other notes	Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.
References: [1]. Mehmedagic A, Verite P, Menager S, Tharasse C, Chabenat C, Andre D, Lafont O. Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats. Biopharm Drug Dispos. 2002 Jul;23(5):191-5. doi: 10.1002/bdd.305. PMID: 12116050.

Quality Control

Quality Control & MSDS

View current batch:

Purity = 99.15%

Chemical structure

5-hydroxypyrazine-2-carboxylic acid