DR 2313
Catalog No.
A4527
PARP inhibitor
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Competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 values are 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro. Brain penetrant.
| Physical Appearance | A crystalline solid |
| Storage | Store at 4°C |
| M.Wt | 182.24 |
| Cas No. | 284028-90-6 |
| Formula | C8H10N2OS |
| Solubility | ≥83.33 mg/mL in DMSO; ≥9.1 mg/mL in H2O |
| Chemical Name | 2-methyl-1,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one |
| SDF | Download SDF |
| Canonical SMILES | CC1=NC(=O)C2=C(N1)CCSC2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| DR 2313 is a competitive inhibitor of PARP1 and PARP2 with IC50 of 0.20 and 0.24 μM respectively. | ||||||
| Targets | PARPK1 | PARP2 | ||||
| IC50 | 0.20 μM | 0.24 μM | ||||
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
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