NFAT Inhibitor
Catalog No.
A4539
NFAT inhibitor
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Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells.
| Physical Appearance | A lyophilized powder |
| Storage | Store at -20°C |
| M.Wt | 1683.93 |
| Cas No. | 249537-73-3 |
| Formula | C75H118N20O22S |
| Solubility | insoluble in EtOH; ≥179.9 mg/mL in DMSO with ultrasonic; ≥34.54 mg/mL in H2O with ultrasonic |
| Chemical Name | (S)-2-((Z)-((S)-2-((Z)-((S)-2-((Z)-(((S)-1-((1Z,3S,4Z,6S,7Z,9S,10Z,12S,13Z,15S,16Z)-1-((S)-1-((S)-2-((Z)-(((S)-1-(2-((Z)-((S)-2-((Z)-((S)-2-amino-1-hydroxy-4-(methylthio)butylidene)amino)-1-hydroxypropylidene)amino)acetyl)pyrrolidin-2-yl)(hydroxy)methylen |
| SDF | Download SDF |
| Canonical SMILES | CC[C@]([C@@](/N=C(O)/[C@](/N=C(O)/[C@]1([H])CCCN1C([C@](/N=C(O)/[C@]2([H])CCCN2C(C/N=C(O)/[C@](/N=C(O)/[C@](N)([H])CCSC)([H])C)=O)([H])CC3=CN=CN3)=O)([H])C(C)C)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/CC(N4CCC[C@@]4([H])/C(O)=N/[C@@](/C(O)=N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
