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- Amyloid β-Protein (1-15)
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- Amyloid β-Protein (1-15)
Amyloid β-Protein (1-15)
Catalog No.
A1003
Principal component of amyloid
Featured Products
Beta-amyloid protein (A beta), a 39-43 amino acid peptide composed of a portion of the transmembrane domain and the extracellular domain of the amyloid precursor protein (APP), is also the principal component of amyloid. Research found that amyloid beta-protein circulates in human blood and in cerebrospinal fluid and is deposited into plaques found in the brains of patients with Alzheimer's disease (AD). The aggregation of the beta-amyloid protein into dense plaques on the exterior of brain cells results in destroys of the synapses and conduction of nerve impulses.
Ref:
1. Sisodia SS, Price DL. Role of the beta-amyloid protein in Alzheimer's disease. FASEB J. 1995 Mar; 9(5): 366-70.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 1826.86 |
Cas No. | 183745-81-5 |
Formula | C78H107N25O27 |
Synonyms | H2N-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-OH |
Solubility | insoluble in EtOH; ≥182.6 mg/mL in DMSO; ≥50.7 mg/mL in H2O |
SDF | Download SDF |
Canonical SMILES | CC(C)C(C(=O)NC(CC1=CNC=N1)C(=O)NC(CC2=CNC=N2)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC4=CNC=N4)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
![Amyloid β-Protein (1-15)](/media/diy/images/struct/A1003.png)
Related Biological Data
![Amyloid β-Protein (1-15) Amyloid β-Protein (1-15)](/media/diy/images/wb/A1003_1.jpg)