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- 1,2,3,4,5,6-Hexabromocyclohexane
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- JAK/STAT Signaling
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- 1,2,3,4,5,6-Hexabromocyclohexane
1,2,3,4,5,6-Hexabromocyclohexane
Catalog No.
A4510
JAK2 tyrosine kinase inhibitor
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Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μM of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM elimates nearly all JAK2 activity. Non-cytotoxic at 100 μM.
Physical Appearance | A solid |
Storage | Store at RT |
M.Wt | 557.54 |
Cas No. | 1837-91-8 |
Formula | C6H6Br6 |
Solubility | insoluble in EtOH; insoluble in H2O; ≥8.22 mg/mL in DMSO with gentle warming |
Chemical Name | 1,2,3,4,5,6-hexabromocyclohexane |
SDF | Download SDF |
Canonical SMILES | C1(C(C(C(C(C1Br)Br)Br)Br)Br)Br |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet