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Ziprasidone

Catalog No.
A3952
5-HT (serotonin)/dopamine receptor antagonist
Grouped product items
SizePriceStock Qty
100mg
$100.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects in preclinical assays predictive of antipsychotic activity. Whereas Ziprasidone is a dopamine antagonist in vitro and in vivo, its most potent action is antagonism of 5-HT2A receptors, where its affinity is an order of magnitude greater than that observed for dopamine D2 sites. Additionally, Ziprasidone inhibits neuronal uptake of 5-HT and norepinephrine comparable to the antidepressant imipramine. Ziprasidone differs from other atypical antipsychotic drugs in several clinically important ways, although further experience is necessary to clarify the significance of these differences.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt412.94
Cas No.146939-27-7
FormulaC21H21ClN4OS
SynonymsGeodon;CP 88059;CP-88059;CP88059
Solubility≥20.65 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
Chemical Name5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one
SDFDownload SDF
Canonical SMILESC1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control