- Home
- Signaling Pathways
- Neuroscience
- AChR
- Tiotropium Bromide
Tiotropium Bromide
Catalog No.
A3874
MAChR M antagonist
Featured Products
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR M) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. This stops signaling between neurons and leads to muscle relaxation. Tiotropium Bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Tiotropium Bromide improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 472.42 |
| Cas No. | 136310-93-5 |
| Formula | C19H22BrNO4S2 |
| Synonyms | Tiopropium |
| Solubility | ≥23.62 mg/mL in DMSO; insoluble in EtOH; ≥33.07 mg/mL in H2O with ultrasonic |
| Chemical Name | (1R,2R,4S,5S,7s)-7-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide |
| SDF | Download SDF |
| Canonical SMILES | O=C(C(C1=C([H])C([H])=C([H])S1)(C2=C([H])C([H])=C([H])S2)O[H])O[C@@]3([H])C([H])([H])[C@]4([H])[N+](C([H])([H])[H])(C([H])([H])[H])[C@@](C3([H])[H])([H])[C@@]5([H])O[C@@]45[H].[Br-] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
