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Tiotropium Bromide

Tiotropium Bromide

Catalog No.

A3874

MAChR M antagonist

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Grouped product items
Size	Price	Stock	Qty
10mM (in 1mL DMSO)	$50.00	In stock
100mg	$133.00	In stock

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Background
Chemical Properties
Quality Control

Background

Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR M) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. This stops signaling between neurons and leads to muscle relaxation. Tiotropium Bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Tiotropium Bromide improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.

Chemical Properties

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	472.42
Cas No.	136310-93-5
Formula	C₁₉H₂₂BrNO₄S₂
Synonyms	Tiopropium
Solubility	≥23.62 mg/mL in DMSO; insoluble in EtOH; ≥33.07 mg/mL in H2O with ultrasonic
Chemical Name	(1R,2R,4S,5S,7s)-7-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide
SDF	Download SDF
Canonical SMILES	O=C(C(C1=C([H])C([H])=C([H])S1)(C2=C([H])C([H])=C([H])S2)O[H])O[C@@]3([H])C([H])([H])[C@]4([H])[N+](C([H])([H])[H])(C([H])([H])[H])[C@@](C3([H])[H])([H])[C@@]5([H])O[C@@]45[H].[Br-]
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.