MK-8033
Catalog No.
A3624
C-MET inhibitor
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MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre- and post-treatment biopsies to evaluate for relevant molecular signatures.
| Storage | Store at -20°C |
| M.Wt | 471.53 |
| Cas No. | 1001917-37-8 |
| Formula | C25H21N5O3S |
| Synonyms | MK 8033;MK8033 |
| Solubility | Soluble in DMSO |
| Chemical Name | 1-(3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide |
| SDF | Download SDF |
| Canonical SMILES | CN1C=C(C2=CN=C3C=CC4=C(C(C3=C2)=O)C=C(CS(=O)(NCC5=CC=CC=N5)=O)C=C4)C=N1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
