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[ CAS No. 941294-57-1 ] {[proInfo.proName]}

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Chemical Structure| 941294-57-1
Chemical Structure| 941294-57-1
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Product Details of [ 941294-57-1 ]

CAS No. :941294-57-1 MDL No. :MFCD09801049
Formula : C6H5BrIN Boiling Point : -
Linear Structure Formula :- InChI Key :CWTODKHZZURTJS-UHFFFAOYSA-N
M.W : 297.92 Pubchem ID :26369928
Synonyms :

Safety of [ 941294-57-1 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 941294-57-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 941294-57-1 ]

[ 941294-57-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 941294-57-1 ]
  • [ 81290-20-2 ]
  • [ 1010422-51-1 ]
YieldReaction ConditionsOperation in experiment
23% With potassium fluoride; copper(l) iodide; In 1-methyl-pyrrolidin-2-one; at 60℃;Inert atmosphere; To a suspension of 5-bromo-2-iodo-4-methylpyridine(1g, 3.36 mmol) in NMP (6mL) with an inert atmosphere of argon, KF (0.585 g, 10.07 mmol), Cul (1.92 g, 10.08 mmol) and CF3SiMe3 (2.49 mL, 15.07 mmol) were added. The resulting solution was stirred overnight at 60C. After cooling, the mixture was poured into 12% aqueous ammonia, and then extracted with Et2O. The organic solutions were combined, dried over MgSO4, filtered and concentrated. Purification of the crude residue by normal phase chromatography (0% to 100%, hexane - diethyl ether) afforded the desired product (23% yield) as a yellow oil.
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