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Chemical Structure| 886362-62-5 Chemical Structure| 886362-62-5
Chemical Structure| 886362-62-5

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CAS No.: 886362-62-5

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Product Details of [ 886362-62-5 ]

CAS No. :886362-62-5
Formula : C16H22BrNO2
M.W : 340.26
SMILES Code : BrC1=CC(C2CCN(C(OC(C)(C)C)=O)CC2)=CC=C1
MDL No. :MFCD04115309
InChI Key :SDAPURUFUOOCTE-UHFFFAOYSA-N
Pubchem ID :40425223

Safety of [ 886362-62-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 886362-62-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 886362-62-5 ]

[ 886362-62-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 50-00-0 ]
  • [ 886362-62-5 ]
  • [ 1187928-92-2 ]
YieldReaction ConditionsOperation in experiment
99% A mixture of 4-(3-bromophenyl)-1-N-Boc piperidine (430 mg, 1.26 mmol), formic acid (5 mL) and formaldehyde (0.5 mL) was heated under microwave irradiation at 150 C for 10 minutes. The cooled reaction mixture was loaded onto a 70 g SCX-2 cartridge which was washed with methanol (200 mL) and then eluted with 2N ammonia in methanol (200 mL). Concentration of the combined basic fractions in vacuo afforded the title compound (318 mg, 99%) as a brown oil. 1H NMR (CDCl3, 300MHz): 7.38-7.36 (m, 1H); 7.35-7.29 (m, 1H); 7.17- 7.14 (m, 2H); 3.03-2.92 (m, 2H); 2.52-2.37 (m, 1H); 2.32 (s, 3H); 2.10-1.99 (m, 2H); 1.87-1.69 (m, 4H).
  • 2
  • [ 24424-99-5 ]
  • [ 1159825-25-8 ]
  • [ 886362-62-5 ]
 

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Technical Information

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[ 886362-62-5 ]

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Related Parent Nucleus of
[ 886362-62-5 ]

Piperidines

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