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CAS No. : | 882518-89-0 | MDL No. : | MFCD27977515 |
Formula : | C17H26O7S | Boiling Point : | No data available |
Linear Structure Formula : | - | InChI Key : | NIPMXQFRYHXBAM-UHFFFAOYSA-N |
M.W : | 374.45 | Pubchem ID : | 59766026 |
Synonyms : |
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Chemical Name : | tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate |
Signal Word: | Warning | Class: | |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | |
Hazard Statements: | H302-H315-H319-H335 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
83.9% | With tetrabutylammomium bromide; potassium hydroxide; In toluene; at 20℃; | Compound 2a (2.954 g, 11.3 mmol) was dissolved in 10 mL of toluene, TBAB (0.181 g, 0.56 mmol), KOH (1.01 g, 18.1 mmol), tert-butyl bromoacetate (2.7 g, 13.6 mmol) . The reaction was stirred at room temperature overnight. After thin layer chromatography (PE: EA = 1:2), the raw material remained. Toluene was concentrated under reduced pressure, and 5 mL of water was added, and the mixture was extracted three times with 15 mL of dichloromethane. Column chromatography (EA) gave 3.4 g of product, yield 83.9%. |
83.9% | With tetrabutylammomium bromide; potassium hydroxide; In toluene; at 20℃; | Compound 2a (2.954 g, 11.3 mmol) was dissolved in 10 mL of toluene, TBAB (0.181 g, 0.56 mmol), KOH (1.01 g, 18.1 mmol), tert-butyl bromoacetate (2.7 g, 13.6 mmol) .The reaction was stirred at room temperature overnight.After thin layer chromatography (PE: EA = 1:2), the raw material remained.The toluene was concentrated under reduced pressure, and 5 mL of water was added, and the mixture was extracted three times with 15 mL of dichloromethane.Column chromatography (EA) gave 3.4 g of product, yield 83.9percent. |