成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 80466-79-1 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 80466-79-1
Chemical Structure| 80466-79-1
Structure of 80466-79-1 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 80466-79-1 ]

Related Doc. of [ 80466-79-1 ]

Alternatived Products of [ 80466-79-1 ]
Product Citations

Product Details of [ 80466-79-1 ]

CAS No. :80466-79-1 MDL No. :MFCD00052554
Formula : C5H6ClNO3S Boiling Point : -
Linear Structure Formula :- InChI Key :GZLPFEYTAAXJCP-UHFFFAOYSA-N
M.W : 195.62 Pubchem ID :2736319
Synonyms :

Calculated chemistry of [ 80466-79-1 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 11
Num. arom. heavy atoms : 5
Fraction Csp3 : 0.4
Num. rotatable bonds : 1
Num. H-bond acceptors : 4.0
Num. H-bond donors : 0.0
Molar Refractivity : 39.52
TPSA : 68.55 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -6.65 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.7
Log Po/w (XLOGP3) : 1.19
Log Po/w (WLOGP) : 2.3
Log Po/w (MLOGP) : -0.11
Log Po/w (SILICOS-IT) : 1.27
Consensus Log Po/w : 1.27

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -2.07
Solubility : 1.65 mg/ml ; 0.00845 mol/l
Class : Soluble
Log S (Ali) : -2.23
Solubility : 1.16 mg/ml ; 0.00595 mol/l
Class : Soluble
Log S (SILICOS-IT) : -2.56
Solubility : 0.541 mg/ml ; 0.00277 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 2.79

Safety of [ 80466-79-1 ]

Signal Word:Danger Class:8
Precautionary Statements:P260-P280-P303+P361+P353-P301+P330+P331-P304+P340+P310-P305+P351+P338+P310 UN#:3261
Hazard Statements:H314 Packing Group:Ⅱ
GHS Pictogram:

Application In Synthesis of [ 80466-79-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 80466-79-1 ]

[ 80466-79-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 80466-79-1 ]
  • [ 272-97-9 ]
  • [ 212690-32-9 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In water; acetonitrile; Petroleum ether; Example 2 Process (a): 1.4 g (10 mmol) of potassium carbonate are added to a solution of 1.2 g (10 mMol) of 1H-imidazo[4,5-c]pyridine in 30 ml of acetonitrile, and the mixture is stirred at 20 C. for 10 minutes. The mixture is then admixed with 1.9 g (10 mmol) of 3,5dimethylisoxazole-4-sulphonyl chloride and stirred at 20 C. for 20 hours. The reaction mixture is subsequently poured into 150 ml of water. The resulting mixture is extracted twice with 70 ml of ethyl acetate each time. The combined organic phases are dried over sodium sulphate and concentrated under reduced pressure. The residue is stirred with 20 ml of petroleum ether and the resulting solid is filtered off land dried. This gives 1.6 g (57% of theory) of 1-(3,5-dimethyl-isoxazole-4-sulphonyl)-1H-imidazo[4,5-c]pyridine as a yellow solid of melting point 130-135 C.
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 80466-79-1 ]

Sulfonyl Chlorides

Chemical Structure| 509074-26-4

[ 509074-26-4 ]

4-(5-Methyl-3-phenylisoxazol-4-yl)benzene-1-sulfonyl chloride

Similarity: 0.69

Chlorides

Chemical Structure| 321309-26-6

[ 321309-26-6 ]

5-Methyl-4-isoxazolesulfonyl chloride

Similarity: 0.86

Chemical Structure| 509074-26-4

[ 509074-26-4 ]

4-(5-Methyl-3-phenylisoxazol-4-yl)benzene-1-sulfonyl chloride

Similarity: 0.69

Chemical Structure| 59340-27-1

[ 59340-27-1 ]

1,3,5-Trimethyl-1H-pyrazole-4-sulfonyl chloride

Similarity: 0.50

Related Parent Nucleus of
[ 80466-79-1 ]

Isoxazoles

Chemical Structure| 321309-26-6

[ 321309-26-6 ]

5-Methyl-4-isoxazolesulfonyl chloride

Similarity: 0.86

Chemical Structure| 509074-26-4

[ 509074-26-4 ]

4-(5-Methyl-3-phenylisoxazol-4-yl)benzene-1-sulfonyl chloride

Similarity: 0.69

Chemical Structure| 181696-35-5

[ 181696-35-5 ]

4-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonic acid

Similarity: 0.52

; ;