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(E)-16-bromo-2,2-dimethyl-4,14-dioxo-3,7,10-trioxa-13-azaheptadec-15-en-17-oic acid[ No CAS ]
Yield
Reaction Conditions
Operation in experiment
100%
In tetrahydrofuran; at 20℃; for 4h;
To a solution of <strong>[5926-51-2]3-bromofuran-2,5-dione</strong> (89 mg, 0.5 mmol) in THF (5 mL), tert-butyl 3-(2- (2-aminoethoxy)ethoxy)propanoate (117 mg, 0.5 mmol) was added. The resulting solution was stirred at r.t. for 4 h. The solvent was removed under vacuum to afford compound 167 (205 mg, theoretical yield). MS ESI m/z calcd for C15H25BrNO7 [M+H]+ 410.07, found 410.03.
In tetrahydrofuran; at 20℃; for 4h;
To a solution of <strong>[5926-51-2]3-bromofuran-2,5-dione</strong> (89 mg, 0.5 mmol) in THF (5 mL), ie/ -butyl 3- (2-(2-aminoethoxy)ethoxy)propanoate (117 mg, 0.5 mmol) was added. The resulting solution was stirred at r.t. for 4 h. The solvent was removed under vacuum to afford compound 19 (205 mg, theoretical yield). MS ESI m/z [M+H]+ 410.03.
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