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With oxygen; ammonium chloride; copper(II) oxide; In 1,4-dioxane; N,N-dimethyl-formamide; at 80℃;Sealed tube;
The reaction vessel was charged with 10 molpercent of CuO, the reaction tube was evacuated and filled with oxygen, and 0.2 mmol of 2-naphthaleneacetonitrile, 0.4 mmol of ammonium chloride, 1 ml of N, N-dimethylformamide and 1 ml of 1, 4-dioxane, the reaction vessel was sealed, reacted at 80 ° C,After the reaction was completed, it was washed with water, extracted with chloroform, dried and concentrated by evaporation under reduced pressure to remove the solvent. The crude product was separated by column chromatography to give the desired product in a yield of 90percent.