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Chemical Structure| 738-70-5 Chemical Structure| 738-70-5
Chemical Structure| 738-70-5

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CAS No.: 738-70-5

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Trimethoprim is a synthetic antibiotic that inhibits dihydrofolate reductase (DHFR) which is necessary for the synthesis of purines, amino acids, and thymidylic acid, with prominent selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively). Trimethoprim is used mainly in the prophylaxis and treatment of urinary tract infections.

Synonyms: NIH 204; BW 56-72; NSC-106568

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Product Details of Trimethoprim

CAS No. :738-70-5
Formula : C14H18N4O3
M.W : 290.32
SMILES Code : NC1=NC=C(CC2=CC(OC)=C(OC)C(OC)=C2)C(N)=N1
Synonyms :
NIH 204; BW 56-72; NSC-106568
MDL No. :MFCD00036761
InChI Key :IEDVJHCEMCRBQM-UHFFFAOYSA-N
Pubchem ID :5578

Safety of Trimethoprim

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338
 

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