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Chemical Structure| 6953-61-3 Chemical Structure| 6953-61-3
Chemical Structure| 6953-61-3

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CAS No.: 6953-61-3

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1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity, But it can induce tubulin acetylation.

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Product Details of [ 1-Naphthohydroxamic acid ]

CAS No. :6953-61-3
Formula : C11H9NO2
M.W : 187.19
SMILES Code : O=C(NO)C1=C2C=CC=CC2=CC=C1
MDL No. :MFCD00059546
InChI Key :JRZGPWOEHDOVMC-UHFFFAOYSA-N
Pubchem ID :23382

Safety of [ 1-Naphthohydroxamic acid ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of [ 1-Naphthohydroxamic acid ]

epigenetics

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.34mL

1.07mL

0.53mL

26.71mL

5.34mL

2.67mL

53.42mL

10.68mL

5.34mL

 

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