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Chemical Structure| 679406-03-2 Chemical Structure| 679406-03-2
Chemical Structure| 679406-03-2

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CAS No.: 679406-03-2

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Product Details of [ 679406-03-2 ]

CAS No. :679406-03-2
Formula : C7H6Cl2N2O2
M.W : 221.04
SMILES Code : O=C(C1=NN=C(Cl)C=C1Cl)OCC
MDL No. :MFCD11521570
InChI Key :MOWPWJUYSRHMHS-UHFFFAOYSA-N
Pubchem ID :53428795

Safety of [ 679406-03-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 679406-03-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 679406-03-2 ]

[ 679406-03-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 679406-03-2 ]
  • [ 41995-29-3 ]
  • [ 1446792-56-8 ]
YieldReaction ConditionsOperation in experiment
29% In acetonitrile; at 130℃; for 24h; Step 1 Ethyl 6-chloro-4-(6-propylpyridin-2-ylamino)pyridazine-3-carboxylate A mixture of ethyl 4,6-dichloropyridazine-3-carboxylate (0.80 g, 3.62 mmol) and <strong>[41995-29-3]6-propylpyridin-2-amine</strong> (739 mg, 5.43 mmol) was dissolved in acetonitrile (4 mL) and heated at 130 C. After 24 h, the reaction mixture was cooled and concentrated in vacuo, then purified by chromatography (silica, 80 g, 0 to 3% acetone in dichloromethane over 15 min, then 3 to 10% acetone in dichloromethane over another 15 min) to give ethyl 6-chloro-4-(6-propylpyridin-2-ylamino)pyridazine-3-carboxylate (335 mg, 1.04 mmol, 29%) as a pale yellow crystalline solid after drying under high vacuum at room temperature. LC-MS 321.1 [M+H]+.
  • 2
  • [ 679406-03-2 ]
  • [ 36936-23-9 ]
  • methyl 6-chloro-4-(5-chloro-6-methylpyridin-2-ylamino)pyridazine-3-carboxylate [ No CAS ]
 

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