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Chemical Structure| 67385-09-5 Chemical Structure| 67385-09-5
Chemical Structure| 67385-09-5

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CAS No.: 67385-09-5

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2-(Boc-amino)ethanethiol is a thiol-containing compound with a Boc-protected amine group. It is used in peptide synthesis and other conjugation applications.

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Product Details of 2-(Boc-amino)ethanethiol

CAS No. :67385-09-5
Formula : C7H15NO2S
M.W : 177.26
SMILES Code : O=C(OC(C)(C)C)NCCS
MDL No. :MFCD00274335
InChI Key :GSJJCZSHYJNRPN-UHFFFAOYSA-N
Pubchem ID :3017761

Safety of 2-(Boc-amino)ethanethiol

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H319-H332-H372-H400
Precautionary Statements:P260-P264-P270-P273-P280-P301+P312+P330-P304+P312-P305+P351+P338-P314-P337+P313-P391-P501
Class:9
UN#:3082
Packing Group:

Application In Synthesis of 2-(Boc-amino)ethanethiol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 67385-09-5 ]

[ 67385-09-5 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 178747-50-7 ]
  • [ 67385-09-5 ]
  • [ 178747-51-8 ]
YieldReaction ConditionsOperation in experiment
80% With potassium carbonate; In N-methyl-acetamide; (b) 3-(2-(N-t-Butoxycarbonylamino)ethylthio)-5-fluoro-1,2-benzisoxazole. To a solution of <strong>[178747-50-7]3-chloro-5-fluoro-1,2-benzisoxazole</strong> (0.83 g) in dimethylformamide (8 ml) was added 2-t-butoxycarbonylaminoethanethiol (0.86 g) and potassium carbonate (0.67 g) with stirring under nitrogen atmosphere, and the mixture was then stirred at 80 C. for 3 hours. The reaction mixture was poured into ice water, extracted with ethyl acetate and the combined extracts were washed with brine and dried over anhydrous magnesium sulphate. After filtration, the solvent was evaporated under reduced pressure and the residue was purified by silica gel column chromatography, to give the title compound (1.21 g, 80%) as a colorless powder. NMR spectrum(CDCl3)deltappm: 1.44(9H,s), 3.41(2H,t,J=6.2 Hz), 3.58(2H,td,J=6.2 Hz,J=6.2 Hz), 4.98(1H,brs), 7.21-7.51(3H,m).
  • 2
  • [ 67385-09-5 ]
  • [ 82632-80-2 ]
  • [ 1333307-92-8 ]
  • 3
  • [ 67385-09-5 ]
  • [ 69655-76-1 ]
  • [ 1588948-20-2 ]
 

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