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Structure of Ranitidine HCl
CAS No.: 66357-59-3
*Storage: {[sel_prStorage]}
*Shipping: {[sel_prShipping]}
Ranitidine HCl is an antagonist of histamine H2-receptor that can inhibit stomach acid production.
Synonyms: Ranitidine (hydrochloride); AH19065
4.5
*For Research Use Only !
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Search for reports by entering the product batch number.
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CAS No. : | 66357-59-3 |
Formula : | C13H23ClN4O3S |
M.W : | 350.86 |
SMILES Code : | CN/C(NCCSCC1=CC=C(CN(C)C)O1)=C\[N+]([O-])=O.Cl |
Synonyms : |
Ranitidine (hydrochloride); AH19065
|
MDL No. : | MFCD00069339 |
GHS Pictogram: |
![]() ![]() |
Signal Word: | Danger |
Hazard Statements: | H303-H315-H317-H319-H334-H335 |
Precautionary Statements: | P261-P264-P271-P272-P280-P284-P302+P352-P304+P340+P312-P305+P351+P338-P333+P313-P337+P313-P342+P311-P403+P233-P405-P501 |
Class: | 6.1 |
UN#: | 2811 |
Packing Group: | Ⅲ |
In Vitro:
Concentration | Treated Time | Description | References |
Guinea-pig isolated right atrium | 0.32, 0.96, 3.2 μMM | 45 minutes | Ranitidine competitively antagonized histamine-induced increases in contraction frequency of the guinea-pig isolated right atrium with a pA2 of 7.2, being 7.9 and 4.5 times more potent than metiamide and cimetidine respectively. | PMC2071551 |
Large mouse cholangiocytes (LMCCs) | 25 μM | 48 hours | To evaluate the effect of H2HR inhibition on mast cell activation, results showed that ranitidine treatment reduced mast cell activation markers and histamine secretion. | PMC9512472 |
Rat hepatocytes | 6.0 μg/mL | 72 hours | To evaluate the effect of ranitidine on hepatocyte proliferation, results showed no significant effect of ranitidine on hepatocyte proliferation in vitro. | PMC2963574 |
In Vivo:
Administration | Dosage | Frequency | Description | References |
Rat | Anaesthetized rat perfused stomach preparation | Intravenous injection | 0.03 to 1.0 mg/kg | Single dose | Ranitidine inhibited histamine- and pentagastrin-induced gastric acid secretion in the perfused stomach preparation of the anaesthetized rat, being 5.2 and 7.0 times more potent on a molar basis than metiamide and cimetidine respectively. | PMC2071551 |
Nude mice | C170 and LIM2412 colon cancer xenograft models | Oral administration in drinking water | 1, 10, 25, 50 or 100 mg/kg | Continued for 23 to 28 days | Ranitidine did not inhibit in vivo growth of C170 but significantly stimulated LIM2412 tumour growth. | PMC2074256 |
Mdr2?/? mice | Primary sclerosing cholangitis (PSC) model | Osmotic minipumps | 10 mg/kg | Once daily for 4 weeks | To evaluate the effect of H2HR antagonist (ranitidine) on PSC-associated damage. Ranitidine treatment reduced liver and biliary damage, fibrosis, and mast cell activation. | PMC6165706 |
ICR mice | HCl/EtOH-induced gastritis model | Oral | 40 mg/kg | Twice a day for two days | To evaluate the anti-inflammatory effect of Ranitidine on HCl/EtOH-induced gastritis, results showed Ranitidine reduced inflammatory lesions in gastric mucosa | PMC7808742 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT02655458 | Multiple Myeloma | Phase 1 | Completed | - | United States, New York ... More >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 10029 Less << |
NCT02125604 | Relapsing-Remitting Multiple S... More >>clerosis Less << | Phase 4 | Completed | - | Germany ... More >> Research Site Augsburg, Germany Research Site Bamburg, Germany Research Site Bayreuth, Germany Research Site Berlin, Germany Research Site Bochum, Germany Research Site Bonn, Germany Research Site Erbach, Germany Research Site Erlangen, Germany Research Site Freiburg, Germany Research Site Hamburg, Germany Research Site Leipzig, Germany Research Site Marburg, Germany Research Site Minden, Germany Research Site Mittweida, Germany Research Site Munchen, Germany Research Site Munster, Germany Research Site Osnabruck, Germany Research Site Potsdam, Germany Research Site Siegen, Germany Less << |
NCT01017198 | Advanced Solid Tumors | Phase 1 | Completed | - | United States, Arizona ... More >> Reseach Facility Scottsdale, Arizona, United States United States, California Reseach Facility Encinitas, California, United States United States, Texas Reseach Facility San Antonio, Texas, United States Less << |
NCT02125604 | - | Completed | - | - | |
NCT03319667 | Plasma Cell Myeloma | Phase 3 | Recruiting | January 2025 | - |
NCT03368664 | Multiple Sclerosis | Phase 3 | Recruiting | March 2025 | - |
NCT02205489 | Relapsing-remitting Multiple S... More >>clerosis Less << | Phase 4 | Completed | - | Belgium ... More >> Investigational Site Number 056002 Brugge, Belgium, 8000 Investigational Site Number 056001 Brussels, Belgium, 1070 France Investigational Site Number 250009 Dijon, France, 21000 Investigational Site Number 250005 Lille Cedex, France, 59037 Investigational Site Number 250001 Lyon Bron, France, 69677 Investigational Site Number 250006 Nancy, France Investigational Site Number 250010 Nantes, France, 44093 Investigational Site Number 250007 Nimes, France, 30029 Investigational Site Number 250008 PARIS Cedex 20, France, 75970 Investigational Site Number 250004 RENNES Cedex 9, France, 35033 Investigational Site Number 250003 Strasbourg Cedex 2, France, 67098 Investigational Site Number 250002 Toulouse, France, 31200 Netherlands Investigational Site Number 528001 Breda, Netherlands, 4818CK Investigational Site Number 528002 Rotterdam, Netherlands, 3079DZ Spain Investigational Site Number 724001 Barcelona, Spain, 08035 Investigational Site Number 724005 Bilbao, Spain, 48013 Investigational Site Number 724002 Madrid, Spain, 28040 Investigational Site Number 724006 Málaga, Spain, 29010 Investigational Site Number 724003 Sevilla, Spain, 41071 Investigational Site Number 724004 Valencia, Spain, 46009 Less << |
NCT00004547 | Abdominal Neoplasm ... More >> Colonic Neoplasm Mesothelioma Peritoneal Neoplasm Less << | Phase 2 | Completed | - | United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less << |
NCT00004547 | - | Completed | - | - | |
NCT01011023 | Unnecessary Nasogastric Tube ... More >> Bowel Anastomosis Less << | Not Applicable | Completed | - | Mexico ... More >> Hospital Infantil de Mexico Mexico, DF, Mexico, 06720 Less << |
NCT03518463 | Pregnancy Related | Not Applicable | Completed | - | Uganda ... More >> Mbarara university of Science and Technology Mbarara, Uganda Less << |
NCT00655850 | Non-Small Cell Lung Cancer | Phase 2 | Completed | - | United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 - 0104 Less << |
NCT03541408 | Delirium | Not Applicable | Recruiting | March 1, 2019 | United States, Illinois ... More >> Rush University Medical Center Recruiting Chicago, Illinois, United States, 60612 Contact: David H Kim, MD ?? 702-588-3470 ?? david_h_kim@rush.edu ?? Contact: Robert J McCarthy, MBA ?? 312-942-7608 ?? robert_j_mccarthy@rush.edu Less << |
NCT02878512 | Success Rate Under Segmental E... More >>pidural Post Operative Pain Less << | Phase 4 | Completed | - | - |
NCT02953210 | Pain, Postoperative ... More >> Anesthesia Complication Nausea Vomiting Ileus Paralytic Hemodynamic Instability Less << | Phase 4 | Unknown | March 2017 | Brazil ... More >> Faculdade de Ciências Médicas da Santa Casa de S?o Paulo Sao Paulo, Brazil, 01221-020 Faculdade de Ciências Médicas da Santa Casa de S?o Paulo Sao Paulo, Brazil, 01333000 Less << |
NCT00655850 | - | Completed | - | - | |
NCT01710592 | Gastro Oesophageal Cancer | Phase 2 | Completed | - | Ireland ... More >> Mercy University Hospital Cork, Ireland Beaumont Hospital Dublin, Ireland Mater Misericordiae University hospital & Mater Private Hospital Dublin, Ireland St James's Hospital Dublin, Ireland The Adelaide and Meath Hospital Dublin, Ireland Waterford Regional Hospital Waterford, Ireland Less << |
NCT03591120 | Delirium | Not Applicable | Recruiting | March 1, 2019 | United States, Illinois ... More >> Rush University Medical Center Recruiting Chicago, Illinois, United States, 60612 Contact: Robert J McCarthy, PharmD ?? 312-942-7608 ?? Robert_J_McCarthy@rush.edu ?? Contact: David H Kim, MD ?? 702-588-3470 ?? david_h_kim@rush.edu Less << |
NCT00924911 | Infections, Bacterial | Phase 1 | Completed | - | United States, New York ... More >> GSK Investigational Site Buffalo, New York, United States, 14202 Less << |
NCT03710304 | Cesarean Section Complications | Not Applicable | Recruiting | June 1, 2020 | Egypt ... More >> Aswan University Recruiting Aswan, Egypt, 81528 Contact: hany f sallam, md ?? 01092440504 ext 002 ?? nahla.elsayed@aswu.ed.eg Less << |
NCT02541643 | - | - | - | United States, New York ... More >> Icahn School.of Medicine at Mount Sinai New York, New York, United States, 10029 Less << | |
NCT01411410 | Neoplasms | Phase 1 | Completed | - | United States, Missouri ... More >> Saint Louis, Missouri, United States, 63110 United States, New York New York, New York, United States, 10065 United States, Texas Houston, Texas, United States, 77030 Less << |
NCT02360696 | - | Unknown | July 2016 | United States, Missouri ... More >> Children's Mercy Recruiting Kansas City, Missouri, United States, 64108 Contact: Nancy E. Lathrom, CCRC ?? 816-855-1860 ?? nelathrom@cmh.edu ?? Contact: Craig A. Friesen, MD ?? 816.234.3016 ?? cfriesen@cmh.edu ?? Sub-Investigator: Jennifer V. Schurman, PhD ?? ?? ?? Principal Investigator: Steven Leeder, PharmD, PhD ?? ?? ?? Principal Investigator: Craig A. Friesen, MD ?? ?? ?? Sub-Investigator: Shui Q. Ye, MD, PhD ?? ?? ?? Sub-Investigator: Nancy E. Lathrom, CCRC ?? ?? ?? Sub-Investigator: Trevor J. Cole, BS Less << | |
NCT02349763 | Hypersensitivity Reaction | Phase 3 | Unknown | August 2015 | Thailand ... More >> Rajavithi Hospital Bangkok, Thailand, 10400 Less << |
NCT01074437 | Hemangioma | Phase 2 | Terminated(Insufficient enroll... More >>ment) Less << | - | United States, Washington ... More >> Seattle Children's Hospital Seattle, Washington, United States, 98105 Less << |
NCT01074437 | - | Terminated(Insufficient enroll... More >>ment) Less << | - | - | |
NCT01734759 | Healthy | Phase 1 | Completed | - | United States, Minnesota ... More >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Less << |
NCT03301454 | Esophageal Cancer, Squamous Ce... More >>ll Less << | Phase 2 | Recruiting | February 2022 | France ... More >> Centre Hospitalier Universitaire Not yet recruiting Amiens, France, 80080 Contact: Vincent HAUTEFEUILLE, MD ?? +33322088849 ?? heutefeuille.vincent@chu-amiens.fr ?? Principal Investigator: Vincent HAUTEFEUILLE, MD ?? ?? ?? Centre Paul Papin Not yet recruiting Angers, France, 49055 Contact: Olivier CAPITAIN, MD ?? +33240679900 ?? olivier.capitain@ico.unicancer.fr ?? Principal Investigator: Olivier CAPITAIN, MD ?? ?? ?? Sub-Investigator: Véronique GUERIN-MEYER, MD ?? ?? ?? Sub-Investigator: Julie VANBOCKSTAEL, MD ?? ?? ?? Centre Fran?ois Baclesse Not yet recruiting Caen, France, 14076 Contact: Marie-Pierre GALAIS, MD ?? +33231455016 ?? mp.galais@baclesse.fr ?? Principal Investigator: Marie-Pierre GALAIS, MD ?? ?? ?? Sub-Investigator: Fran?oise POLYCARPE-OSAER, MD ?? ?? ?? Sub-Investigator: Aurélie PARZY, MD ?? ?? ?? Sub-Investigator: Stéphane CORBINAIS, MD ?? ?? ?? Centre Oscar Lambret Recruiting Lille, France, 59020 Contact: Farid EL HAJBI, MD ?? +33320295266 ?? f-elhajbi@o-lambret.fr ?? Sub-Investigator: Frederik LAESTADIUS, MD ?? ?? ?? Sub-Investigator: Diane PANNIER, MD ?? ?? ?? Sub-Investigator: Natacha STERN, MD ?? ?? ?? Sub-Investigator: Nicolas PENEL, PhD ?? ?? ?? Sub-Investigator: Thomas RYCKEWAERT, MD ?? ?? ?? Centre René Gauducheau Not yet recruiting Nantes, France, 44805 Contact: Olivier CAPITAIN, MD ?? +33240679900 ?? olivier.capitain@ico.unicancer.fr ?? Sub-Investigator: Hélène SENELLART, MD ?? ?? ?? Sub-Investigator: Sandrine HIRET, MD ?? ?? ?? Principal Investigator: Olivier CAPITAIN, MD ?? ?? ?? Sub-Investigator: Judith RAIMBOURG, MD ?? ?? ?? Centre Armoricain de Radiothérapie, Imagerie médicale et Oncologie Not yet recruiting Plérin, France, 22190 Contact: Pierre-Luc ETIENNE, MD ?? +33296752216 ?? pl.etienne@cario-sante.fr ?? Principal Investigator: Pierre-Luc ETIENNE, MD ?? ?? ?? Sub-Investigator: Jér?me MARTIN-BABAU, MD ?? ?? ?? Sub-Investigator: Dominique BESSON, MD ?? ?? ?? Sub-Investigator: Anne-Claire HARDY-BESSARD, MD ?? ?? ?? Centre Eugène Marquis Not yet recruiting Rennes, France, 35042 Contact: Julien EDELINE, Pr ?? +33299253000 ?? j.edeline@rennes.unicancer.fr ?? Principal Investigator: Samuel LE SOURD, MD ?? ?? ?? Sub-Investigator: Anais BODERE, MD ?? ?? ?? Sub-Investigator: Julien EDELINE, PhD ?? ?? ?? Sub-Investigator: Claire LARIBLE, MD ?? ?? ?? Sub-Investigator: Fanny LE DU, MD ?? ?? ?? Sub-Investigator: Astrid LIEVRE, MD ?? ?? ?? Sub-Investigator: Marc PRACHT, MD Less << |
NCT01048229 | Early-stage Parkinson's Diseas... More >>e Less << | Phase 4 | Terminated(recruitment) | - | - |
NCT00551122 | Brain and Central Nervous Syst... More >>em Tumors Extragonadal Germ Cell Tumor Ovarian Cancer Testicular Germ Cell Tumor Less << | Phase 1 Phase 2 | Unknown | - | United Kingdom ... More >> Queen Elizabeth Hospital at University Hospital of Birmingham NHS Trust Recruiting Birmingham, England, United Kingdom, B15 2TH Contact: Michael H. Cullen, MD ?? 0121-627-2444 ?? ?? Southampton General Hospital Recruiting Southampton, England, United Kingdom, SO16 6YD Contact: G. Mead, MD ?? 44-23-8079-8639 ?? ?? Royal Marsden - Surrey Recruiting Sutton, England, United Kingdom, SM2 5PT Contact: Robert A. Huddart, MD ?? 44-20-8661-3457 ?? robert.huddart@icr.ac.uk Less << |
NCT00855660 | Pharmacology, Clinical | Phase 1 | Completed | - | Germany ... More >> K?ln, Nordrhein-Westfalen, Germany, 51147 Less << |
NCT01032655 | Helicobacter Pylori Infection | Phase 4 | Completed | - | Taiwan ... More >> National Taiwan University Hospital Taipei, Taiwan, 10002 Less << |
NCT01248962 | Ovarian Cancer ... More >> Fallopian Tube Cancer Peritoneal Cancer Less << | Phase 2 | Completed | - | United States, New York ... More >> Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 Less << |
NCT00885417 | H. Pylori Infection | Phase 4 | Completed | - | Taiwan ... More >> National Taiwan University Hospital Taipei, Taiwan, 10002 Less << |
NCT00001910 | - | Completed | - | United States, Maryland ... More >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Less << | |
NCT03241602 | Decrease Post Laproscopy Shoul... More >>der and Abdominal Pain Less << | Phase 4 | Completed | - | Egypt ... More >> Faculty of medicine CAIRO UNIVERISTY Cairo, Egypt Less << |
NCT00443963 | Dyspepsia | Phase 4 | Terminated(The Principal Inves... More >>tigator is no longer affiliated with the Study Site.) Less << | - | United States, District of Col... More >>umbia Washington Hospital Center 110 Irving St. NW, Washington, District of Columbia, United States, 20010 Less << |
NCT00985608 | Helicobacter Pylori Infection | Phase 2 | Unknown | September 2009 | Italy ... More >> Institute of Internal Medicine - Catholic University Recruiting Rome, Italy, 00168 Contact: Giovanni Cammarota, MD ?? 0039-06-30155948 ?? gcammarota@rm.unicatt.it ?? Principal Investigator: Giovanni Cammarota, MD Less << |
NCT03644550 | Mesothelioma | Phase 2 | Recruiting | February 28, 2023 | United States, Maryland ... More >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office ?? 888-624-1937 Less << |
NCT00285688 | - | Unknown | December 2008 | Thailand ... More >> Rajavithi Hospital Recruiting Ratchathewi, Bangkok, Thailand, 10400 Contact: Piyathida Harnsomboonrana, M.D. ?? 6618423854 ?? pboontee@yahoo.com Less << | |
NCT02570529 | Pancreatic Ductal Adenocarcino... More >>ma Less << | Phase 4 | Unknown | February 2018 | - |
NCT01866449 | Glioblastoma Multiforme (GBM) ... More >>WHO Grade IV Less << | Phase 2 | Completed | - | Germany ... More >> H?matologisch onkologische Praxis Augsburg, Germany, 86150 Stiftungsklinikum Mittelrhein GmbH Koblenz, Germany, 56068 Lars Bullinger, MD Ulm, Germany, 89081 Less << |
NCT01028807 | Early Feeding ... More >> Bowel Anastomosis Less << | Not Applicable | Completed | - | Mexico ... More >> Hospital Infantil de Mexico Mexico Df, DF, Mexico, 06720 Less << |
NCT01083537 | Ovarian Cancer ... More >> Peritoneal Cancer Fallopian Tube Cancer Bowel Obstruction Less << | Phase 1 Phase 2 | Terminated(Slow accrual) | - | Canada, Ontario ... More >> Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Less << |
NCT03715881 | Non-Arteritic Anterior Ischemi... More >>c Optic Neuropathy (NAION) Less << | Phase 2 | Recruiting | March 1, 2019 | Iran, Islamic Republic of ... More >> Ophthalmic Research Center Recruiting Tehran, Iran, Islamic Republic of Contact: Homayon Nikkhah, MD ?? 009822591616 ?? labbafi@hotmail.com Less << |
NCT00037570 | Peptic Ulcer Hemorrhage | Phase 2 | Completed | - | United States, California ... More >> Los Angeles, California, United States, 90073 San Diego, California, United States, 62103-8401 United States, Ohio Cincinnati, Ohio, United States, 45267-0595 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19140 United States, Texas Houston, Texas, United States, 77030-4211 United States, Virginia Norfolk, Virginia, United States, 23507 Less << |
NCT02441894 | Prostate Cancer | Phase 4 | Completed | - | Japan ... More >> Investigational Site Number 392004 Chuo-ku, Chiba, Japan Investigational Site Number 392008 Kita-gun, Japan Investigational Site Number 392007 Kobe-shi, Hyogo, Japan Investigational Site Number 392005 Nagakute-shi, Aichi, Japan Investigational Site Number 392006 Osaka Sayama-shi, Osaka, Japan Investigational Site Number 392001 Shinjuku-ku, Tokyo, Japan Investigational Site Number 392002 Yokohama-shi, Kanagawa, Japan Investigational Site Number 392009 Yokohama-shi, Japan Less << |
NCT00199342 | Stage IV Melanoma | Phase 1 Phase 2 | Terminated(Occurrence of 2 dos... More >>e-limiting toxicities at the initial dose level (60 mg/m2) in Part I.) Less << | - | United States, Alabama ... More >> Comprehensive Cancer Center- University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, Florida H. Lee Moffitt Cancer Center Tampa, Florida, United States, 22612 Less << |
NCT02555852 | - | Completed | - | Canada, Quebec ... More >> Lady Davis Institute for Medical Research, Jewish General Hospital Montreal, Quebec, Canada, H3T1E2 Less << | |
NCT00247715 | Dyspepsia Gas... More >>trointestinal Diseases Less << | Not Applicable | Completed | - | Netherlands ... More >> Radboud University Nijmegen Medical Center Nijmegen, Gelderland, Netherlands, 6500 HB Maastricht University Maastricht, Limburg, Netherlands, 6200 MB UMC Utrecht Utrecht, Netherlands Less << |
NCT02169856 | Postoperative Nausea and Vomit... More >>ing Less << | Not Applicable | Completed | - | Pakistan ... More >> Benazir Bhutto Hospital Rawalpindi. Rawalpindi, Punjab, Pakistan, 46000 Less << |
NCT00930670 | Coronary Artery Disease | Phase 4 | Completed | - | Canada, Quebec ... More >> Institut Universitaire de Cardiologie et de Pneumologie de Quebec Quebec City, Quebec, Canada, G1V4G5 Less << |
NCT03619408 | - | Not yet recruiting | July 2020 | - | |
NCT02441673 | Post Anaesthetic Shivering | Phase 2 | Not yet recruiting | June 2019 | - |
NCT01209455 | Poisoning | Not Applicable | Unknown | September 2012 | United Kingdom ... More >> Clinical Research Facility, Royal Infirmary of Edinburgh Recruiting Edinburgh, Midlothian, United Kingdom, EH16 4SA Principal Investigator: Euan A Sandilands, MRCP BSc Less << |
NCT00220909 | Patients Undergoing Elective C... More >>oronary Artery Bypass Graft Less << | Phase 4 | Terminated(Recruitment slow) | - | United States, Pennsylvania ... More >> Temple University School of Medicine Philadelphia, Pennsylvania, United States, 19140 Less << |
NCT02999633 | T-cell Type Acute Leukemia-Pre... More >>cursor T-lymphoblastic Lymphoma/Leukaemia Less << | Phase 2 | Terminated(Due to an unsatisfa... More >>ctory benefit/risk ratio, as specified in & 14.8.1 of the protocol, Sanofi decided to stop enrollment and terminate ACT14596 prematurely) Less << | - | United States, Georgia ... More >> Investigational Site Number 8400002 Atlanta, Georgia, United States, 30342 United States, New Jersey Investigational Site Number 8400003 Hackensack, New Jersey, United States, 07601 United States, Texas Investigational Site Number 8400001 Houston, Texas, United States, 77030 Finland Investigational Site Number 2460001 Helsinki, Finland, 00029 France Investigational Site Number 2500005 Nantes Cedex 01, France, 44093 Investigational Site Number 2500001 Paris Cedex 10, France, 75475 Investigational Site Number 2500004 Pessac, France, 33600 Investigational Site Number 2500002 Pierre Benite, France, 69310 Hungary Investigational Site Number 3480001 Budapest, Hungary, 1083 Investigational Site Number 3480003 Budapest, Hungary, 1097 Investigational Site Number 3480002 Debrecen, Hungary, 4032 Italy Investigational Site Number 3800001 Bergamo, Italy, 24127 Investigational Site Number 3800004 Brescia, Italy, 25123 Lithuania Investigational Site Number 4400001 Vilnius, Lithuania, 08661 Russian Federation Investigational Site Number 6430003 Moscow, Russian Federation, 117198 Investigational Site Number 6430004 Moscow, Russian Federation, 125167 Investigational Site Number 6430001 Moscow, Russian Federation, 129301 Less << |
NCT01274130 | Healthy Adult | Not Applicable | Completed | - | Korea, Republic of ... More >> Severance Hospital Seoul, Korea, Republic of, 120-752 Less << |
NCT02966665 | Chronic Obstructive Pulmonary ... More >>Disease Pulmonary Artery Hypertension Heart Failure Hypertension Less << | Phase 1 | Recruiting | August 2020 | United States, Utah ... More >> George E Wahlen VA Medical Center Recruiting Salt Lake City, Utah, United States, 84132 Contact: Russell Richardson, Ph.D. ?? 801-582-1565 ?? r.richardson@hsc.utah.edu ?? Contact: Ashley Nelson, MD ?? 801-582-1565 ext 4127 ?? ash.nelson@hsc.utah.edu Less << |
NCT02123498 | Eustachian Tube Dysfunction ... More >> Laryngopharyngeal Reflux Less << | Phase 4 | Withdrawn(IRB not approved) | - | United States, California ... More >> 11234 Anderson Street Loma Linda, California, United States, 92354 1895 Orange Tree Lane, Suite 102 Redlands, California, United States, 92374 Less << |
NCT00223691 | Autonomic Failure ... More >> Orthostatic Hypotension Less << | Phase 1 | Completed | - | United States, Tennessee ... More >> Vanderbilt University Nashville, Tennessee, United States, 37232 Less << |
NCT02004197 | Helicobacter Pylori [H. Pylori... More >>] as the Cause of Diseases Less << | Phase 2 Phase 3 | Completed | - | Pakistan ... More >> clinical trial was conducted in high risk areas of Pakistan such as Karachi, Bahawalpur, Islamabad and Rawalpindi at Shifa-Ul-Mulk Memorial Hospital, Hamdrad University Karachi, Bahawalpur Victoria Hospital and Nawaz Salik Hospital respectively Karachi, Pakistan Shifa Ul MUlk Memorial Hospital Karachi, Pakistan Less << |
NCT00131248 | Gastroesophageal Reflux | Phase 3 | Completed | - | United States, Texas ... More >> Memorial Hermann Children's Hospital Houston, Texas, United States, 77030 Less << |
NCT01261546 | Parapneumonic Pleural Effusion... More >> Empyema Less << | Phase 2 | Completed | - | Spain ... More >> Hospital Carlos Haya Malaga, Andalucia, Spain Complejo Hospitalario Toledo Toledo, Castilla La Mancha, Spain Hospital Principe de Asturias Alcalá de Henares, Madrid, Spain Hospital Universitario de Getafe Getafe, Madrid, Spain Hospital Infanta Sofia San Sebastián de los Reyes, Madrid, Spain, 28014 Hospital Infantil La Paz Madrid, Spain, 28037 Hospital Ramón y Cajal Madrid, Spain Hospital Universitario Gregorio Mara?ón Madrid, Spain Less << |
NCT02258815 | Neuroblastoma Recurrent | Phase 2 | Unknown | December 2015 | Austria ... More >> University Hospital Graz Recruiting Graz, Austria, 8036 Contact: Wolfgang Schwinger, MD, PhD ?? +43 31638512605 ?? wolfgang.schwinger@medunigraz.at ?? Principal Investigator: Wolfgang Schwinger, MD, PhD ?? ?? ?? St. Anna Childrens Hospital Recruiting Vienna, Austria, 1090 Contact: Ruth Ladenstein, MD, PhD ?? 43 1 40470 3250 ?? ruth.ladenstein@ccri.at ?? Principal Investigator: Ruth Ladenstein, MD, PhD ?? ?? ?? Germany University Hospital Greifswald Recruiting Greifswald, Germany, 17475 Contact: Holger Lode, MD, PhD ?? +49 3834866301 ?? lode@uni-greifswald.de ?? Principal Investigator: Holger Lode, MD, PhD ?? ?? ?? University Hospital Tuebingen Recruiting Tuebingen, Germany, 72076 Contact: Peter Lang, MD, PhD ?? +4970712983781 ?? peter.lang@med.uni-tuebingen.de ?? Principal Investigator: Peter Lang, MD, PhD Less << |
NCT00161200 | Esophageal Metaplasia | Phase 3 | Terminated(slow accrual) | - | United States, New Jersey ... More >> Cancer Institute of New Jersey New Brunswick, New Jersey, United States, 08901 Less << |
NCT01332630 | Breast Cancer | Phase 2 | Completed | - | United States, Texas ... More >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less << |
NCT01332630 | - | Completed | - | - | |
NCT00131248 | - | Completed | - | - | |
NCT02703896 | Pulmonary Aspiration of Gastri... More >>c Contents Less << | Phase 4 | Completed | - | - |
NCT00030992 | - | Completed | - | - | |
NCT00030992 | Renal Cell Carcinoma | Phase 2 | Completed | - | United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less << |
NCT03667703 | Congenital Heart Disease ... More >> Upper Gastrointestinal Bleeding Stress Ulcer Infection Less << | Not Applicable | Not yet recruiting | June 30, 2021 | United States, Massachusetts ... More >> Boston Children's Hospital Not yet recruiting Boston, Massachusetts, United States, 02115 Contact: Kimberly I Mills, MD ?? 617-355-7866 ?? kimberly.mills@cardio.chboston.org ?? Contact: Ben D Albert, MD ?? 617-355-7866 ?? ben.albert@childrens.harvard.edu Less << |
NCT03583567 | Protamine Adverse Reaction | Phase 4 | Recruiting | December 1, 2020 | Thailand ... More >> Siriraj Hospital Recruiting Bangkok, Thailand, 10700 Contact: Sirilak Suksompoong, MD ?? ?? ssuksompong5@gmail.com Less << |
NCT03468777 | Healthy | Phase 1 | Terminated(The study has been ... More >>terminated due to pending data analysis) Less << | - | Belgium ... More >> Clinical Pharmacology Unit Merksem, Belgium, 2170 Less << |
NCT00585351 | - | Completed | - | - | |
NCT00585351 | Stroke | Not Applicable | Completed | - | United States, Iowa ... More >> University of Iowa Iowa City, Iowa, United States, 52242 Less << |
NCT00590928 | Critically Ill Patients ... More >> Indication for Stress Ulcer Prophylaxis Less << | Phase 4 | Completed | - | Austria ... More >> Medical University of Vienna, Department of Medicine III, ICU Vienna, Austria, 1090 Less << |
NCT00000964 | HIV Infections | Phase 1 | Completed | - | United States, Maryland ... More >> Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States, 21205 Less << |
NCT00405119 | Gastroesophageal Reflux Diseas... More >>e Reflux, Gastroesophageal Less << | Phase 2 | Completed | - | Australia, New South Wales ... More >> GSK Investigational Site Randwick, New South Wales, Australia, 2031 Australia, Queensland GSK Investigational Site Herston, Queensland, Australia, 4006 Less << |
NCT03140033 | Hemorrhage Postpartum | Phase 2 | Recruiting | May 2017 | Egypt ... More >> Ain shams maternity hospital Recruiting Cairo, Egypt Contact: Mohamed Fathy, M.B.B.Ch ?? 00201099984100 ?? Mohamedfathy31085@gmail.com ?? Contact: AMR Helmy, MD.MRCOG ?? 00201227900014 ?? am_helmy77@hotmail.com Less << |
NCT03011463 | Pharmacokinetics ... More >> Inhibition Enzyme Drug Interaction Potentiation Less << | Phase 1 | Completed | - | - |
NCT00702871 | Ventilator Associated Pneumoni... More >>a Etiological Organisms Antimicrobial Drug Susceptibility Pattern Stress Ulcer Prophylaxis Less << | Phase 4 | Completed | - | India ... More >> Maulana Azad Medical College and Lok Nayak Hospital Delhi, India, 110002 Less << |
NCT01976078 | - | Completed | - | United States, California ... More >> Children's Hospital Los Angeles Los Angeles, California, United States, 90027 Less << | |
NCT00668317 | - | Terminated(Primary care physic... More >>ians began prescribing antacid therapy for chronic cough) Less << | - | - | |
NCT00668317 | Cough | Phase 3 | Terminated(Primary care physic... More >>ians began prescribing antacid therapy for chronic cough) Less << | - | United Kingdom ... More >> Clinical Trials Unit , Cardiovascular and respiratory studies, Castle Hill Hospital Cottingham, East Yorkshire, United Kingdom, HU16 5JQ Less << |
NCT02172417 | Healthy | Phase 1 | Completed | - | - |
NCT00633412 | NSAID Associated Gastric Ulcer... More >>s Less << | Phase 3 | Completed | - | - |
NCT00839306 | Gastroesophageal Reflux Diseas... More >>e (GERD) Less << | Phase 3 | Completed | - | United States, Illinois ... More >> Associates, Ltd. Moline, Illinois, United States, 61265 Midwest Clinical Moline, Illinois, United States, 61265 Research Moline, Illinois, United States, 61265 Moline, Illinois, United States, 61265 Less << |
NCT02733640 | Antiplatelet Effect | Not Applicable | Completed | - | Korea, Republic of ... More >> Seoul National University Bundang Hospital Seongnam, Gyeonggi-do, Korea, Republic of, 463-707 Less << |
NCT00838526 | Gastroesophageal Reflux Diseas... More >>e (GERD) Less << | Phase 3 | Completed | - | United States, Illinois ... More >> Ltd. Moline, Illinois, United States, 61265 Midwest Clinical Moline, Illinois, United States, 61265 Research Associates Moline, Illinois, United States, 61265 Moline, Illinois, United States, 61265 Less << |
NCT00839306 | - | Completed | - | - | |
NCT00838526 | - | Completed | - | - | |
NCT01908257 | Healthy | Phase 1 | Completed | - | United States, California ... More >> Cypress, California, United States, 90630 Less << |
NCT01392755 | Healthy Volunteer | Phase 1 | Completed | - | United States, Kansas ... More >> Lenexa, Kansas, United States, 66219 Less << |
NCT01538797 | Reflux Oesophagitis | Phase 1 | Completed | - | United Kingdom ... More >> Hammersmith Medicines Research London, United Kingdom, NW10 7EW Less << |
NCT00401752 | Gastric Ulcer | Phase 3 | Completed | - | China, Fujian ... More >> Research Site Fuzhou, Fujian, China China, Guangdong Research Site Guangzhou, Guangdong, China China, Hubei Research Site Wuhan, Hubei, China China, Jiangsu Research Site Suzhou, Jiangsu, China China, Liaoning Research Site Shenyang, Liaoning, China China, Shanxi Research Site Xi'an, Shanxi, China China Research Site Beijing, China Research Site Shanghai, China Hong Kong Research Site Hong Kong, Hong Kong Less << |
NCT00633672 | NSAID Associated Gastric Ulcer... More >>s Less << | Phase 3 | Completed | - | - |
NCT03145012 | Cancer | Phase 4 | Not yet recruiting | April 30, 2019 | Canada, Nova Scotia ... More >> Nova Scotia Health Authority Not yet recruiting Halifax, Nova Scotia, Canada, B3H 1V7 Contact: Lisa Barrett, MD ?? ?? lisa.barrett@nshealth.ca ?? Contact: Jill Moore ?? ?? jill.moore@nshealth.ca Less << |
NCT02170792 | Healthy | Phase 1 | Completed | - | - |
NCT01682408 | Pharmacokinetics | Phase 1 | Completed | - | United States, Kansas ... More >> Overland Park, Kansas, United States Less << |
NCT00401752 | - | Completed | - | - | |
NCT01737840 | Dyspepsia | Phase 4 | Completed | - | Turkey ... More >> Akdeniz University Antalya, Turkey, 07050 Less << |
NCT00002106 | HIV Infections | PHASE2 | COMPLETED | - | Pacific Oaks Med Group, Sherma... More >>n Oaks, California, 91403, United States|Community Research Initiative, Coral Gables, Florida, 33146, United States|Duke Univ Med Ctr, Durham, North Carolina, 27710, United States|Houston Clinical Research Network, Houston, Texas, 77006, United States Less << |
NCT01539655 | Medullary Thyroid Cancer | Phase 1 | Completed | - | United States, Kansas ... More >> Research Site Overland Park, Kansas, United States Less << |
NCT00527878 | JOB's Syndrome ... More >> Hyper-IgE Recurrent Infection Syndrome Immune Deficiency Less << | Phase 2 | Terminated(Failure to enroll a... More >>dequate patient numbers due to small number of eligible patients) Less << | - | United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less << |
NCT00527878 | - | Terminated(Failure to enroll a... More >>dequate patient numbers due to small number of eligible patients) Less << | - | - | |
NCT01896557 | Coronary Artery Disease ... More >> Drug Interaction Potentiation Less << | Phase 4 | Completed | - | - |
NCT02700087 | Laryngomalacia ... More >> Acid Reflux Stridor Less << | Not Applicable | Withdrawn | February 2017 | United States, California ... More >> Lucile Packard Children's Hospital Stanford Palo Alto, California, United States, 94304 Less << |
NCT02197143 | Dyspepsia | Phase 4 | Completed | - | Turkey ... More >> Pamukkale Universty Denizli, Turkey, 20000 Less << |
NCT00247130 | Peptic Ulcers | Phase 4 | Withdrawn(Superiority of iv om... More >>eprazole to ranitidine has already been proven by others.) Less << | - | Japan ... More >> Department of Internal Medicine, Keio University School of Medicine Tokyo, Japan, 1608582 Less << |
NCT01131702 | Healthy | Phase 1 | Completed | - | Canada, Quebec ... More >> Anapharm Inc. Montreal, Quebec, Canada, G1V 2K8 Less << |
NCT02195804 | Healthy | Phase 1 | Completed | - | - |
NCT01737840 | - | Completed | - | - | |
NCT01896557 | - | Completed | - | - |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.85mL 0.57mL 0.29mL |
14.25mL 2.85mL 1.43mL |
28.50mL 5.70mL 2.85mL |
[4]Gaginella TS, Bauman JH. Ranitidine hydrochloride. Drug Intell Clin Pharm. 1983 Dec;17(12):873-85