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Chemical Structure| 66357-59-3 Chemical Structure| 66357-59-3

Structure of Ranitidine HCl
CAS No.: 66357-59-3

Chemical Structure| 66357-59-3

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CAS No.: 66357-59-3

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Ranitidine HCl is an antagonist of histamine H2-receptor that can inhibit stomach acid production.

Synonyms: Ranitidine (hydrochloride); AH19065

4.5 *For Research Use Only !

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Product Details of Ranitidine HCl

CAS No. :66357-59-3
Formula : C13H23ClN4O3S
M.W : 350.86
SMILES Code : CN/C(NCCSCC1=CC=C(CN(C)C)O1)=C\[N+]([O-])=O.Cl
Synonyms :
Ranitidine (hydrochloride); AH19065
MDL No. :MFCD00069339

Safety of Ranitidine HCl

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H303-H315-H317-H319-H334-H335
Precautionary Statements:P261-P264-P271-P272-P280-P284-P302+P352-P304+P340+P312-P305+P351+P338-P333+P313-P337+P313-P342+P311-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Ranitidine HCl

GPCR

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
Guinea-pig isolated right atrium 0.32, 0.96, 3.2 μMM 45 minutes Ranitidine competitively antagonized histamine-induced increases in contraction frequency of the guinea-pig isolated right atrium with a pA2 of 7.2, being 7.9 and 4.5 times more potent than metiamide and cimetidine respectively. PMC2071551
Large mouse cholangiocytes (LMCCs) 25 μM 48 hours To evaluate the effect of H2HR inhibition on mast cell activation, results showed that ranitidine treatment reduced mast cell activation markers and histamine secretion. PMC9512472
Rat hepatocytes 6.0 μg/mL 72 hours To evaluate the effect of ranitidine on hepatocyte proliferation, results showed no significant effect of ranitidine on hepatocyte proliferation in vitro. PMC2963574

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Rat Anaesthetized rat perfused stomach preparation Intravenous injection 0.03 to 1.0 mg/kg Single dose Ranitidine inhibited histamine- and pentagastrin-induced gastric acid secretion in the perfused stomach preparation of the anaesthetized rat, being 5.2 and 7.0 times more potent on a molar basis than metiamide and cimetidine respectively. PMC2071551
Nude mice C170 and LIM2412 colon cancer xenograft models Oral administration in drinking water 1, 10, 25, 50 or 100 mg/kg Continued for 23 to 28 days Ranitidine did not inhibit in vivo growth of C170 but significantly stimulated LIM2412 tumour growth. PMC2074256
Mdr2?/? mice Primary sclerosing cholangitis (PSC) model Osmotic minipumps 10 mg/kg Once daily for 4 weeks To evaluate the effect of H2HR antagonist (ranitidine) on PSC-associated damage. Ranitidine treatment reduced liver and biliary damage, fibrosis, and mast cell activation. PMC6165706
ICR mice HCl/EtOH-induced gastritis model Oral 40 mg/kg Twice a day for two days To evaluate the anti-inflammatory effect of Ranitidine on HCl/EtOH-induced gastritis, results showed Ranitidine reduced inflammatory lesions in gastric mucosa PMC7808742

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02655458 Multiple Myeloma Phase 1 Completed - United States, New York ... More >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 10029 Less <<
NCT02125604 Relapsing-Remitting Multiple S... More >>clerosis Less << Phase 4 Completed - Germany ... More >> Research Site Augsburg, Germany Research Site Bamburg, Germany Research Site Bayreuth, Germany Research Site Berlin, Germany Research Site Bochum, Germany Research Site Bonn, Germany Research Site Erbach, Germany Research Site Erlangen, Germany Research Site Freiburg, Germany Research Site Hamburg, Germany Research Site Leipzig, Germany Research Site Marburg, Germany Research Site Minden, Germany Research Site Mittweida, Germany Research Site Munchen, Germany Research Site Munster, Germany Research Site Osnabruck, Germany Research Site Potsdam, Germany Research Site Siegen, Germany Less <<
NCT01017198 Advanced Solid Tumors Phase 1 Completed - United States, Arizona ... More >> Reseach Facility Scottsdale, Arizona, United States United States, California Reseach Facility Encinitas, California, United States United States, Texas Reseach Facility San Antonio, Texas, United States Less <<
NCT02125604 - Completed - -
NCT03319667 Plasma Cell Myeloma Phase 3 Recruiting January 2025 -
NCT03368664 Multiple Sclerosis Phase 3 Recruiting March 2025 -
NCT02205489 Relapsing-remitting Multiple S... More >>clerosis Less << Phase 4 Completed - Belgium ... More >> Investigational Site Number 056002 Brugge, Belgium, 8000 Investigational Site Number 056001 Brussels, Belgium, 1070 France Investigational Site Number 250009 Dijon, France, 21000 Investigational Site Number 250005 Lille Cedex, France, 59037 Investigational Site Number 250001 Lyon Bron, France, 69677 Investigational Site Number 250006 Nancy, France Investigational Site Number 250010 Nantes, France, 44093 Investigational Site Number 250007 Nimes, France, 30029 Investigational Site Number 250008 PARIS Cedex 20, France, 75970 Investigational Site Number 250004 RENNES Cedex 9, France, 35033 Investigational Site Number 250003 Strasbourg Cedex 2, France, 67098 Investigational Site Number 250002 Toulouse, France, 31200 Netherlands Investigational Site Number 528001 Breda, Netherlands, 4818CK Investigational Site Number 528002 Rotterdam, Netherlands, 3079DZ Spain Investigational Site Number 724001 Barcelona, Spain, 08035 Investigational Site Number 724005 Bilbao, Spain, 48013 Investigational Site Number 724002 Madrid, Spain, 28040 Investigational Site Number 724006 Málaga, Spain, 29010 Investigational Site Number 724003 Sevilla, Spain, 41071 Investigational Site Number 724004 Valencia, Spain, 46009 Less <<
NCT00004547 Abdominal Neoplasm ... More >> Colonic Neoplasm Mesothelioma Peritoneal Neoplasm Less << Phase 2 Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT00004547 - Completed - -
NCT01011023 Unnecessary Nasogastric Tube ... More >> Bowel Anastomosis Less << Not Applicable Completed - Mexico ... More >> Hospital Infantil de Mexico Mexico, DF, Mexico, 06720 Less <<
NCT03518463 Pregnancy Related Not Applicable Completed - Uganda ... More >> Mbarara university of Science and Technology Mbarara, Uganda Less <<
NCT00655850 Non-Small Cell Lung Cancer Phase 2 Completed - United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 - 0104 Less <<
NCT03541408 Delirium Not Applicable Recruiting March 1, 2019 United States, Illinois ... More >> Rush University Medical Center Recruiting Chicago, Illinois, United States, 60612 Contact: David H Kim, MD ?? 702-588-3470 ?? david_h_kim@rush.edu ?? Contact: Robert J McCarthy, MBA ?? 312-942-7608 ?? robert_j_mccarthy@rush.edu Less <<
NCT02878512 Success Rate Under Segmental E... More >>pidural Post Operative Pain Less << Phase 4 Completed - -
NCT02953210 Pain, Postoperative ... More >> Anesthesia Complication Nausea Vomiting Ileus Paralytic Hemodynamic Instability Less << Phase 4 Unknown March 2017 Brazil ... More >> Faculdade de Ciências Médicas da Santa Casa de S?o Paulo Sao Paulo, Brazil, 01221-020 Faculdade de Ciências Médicas da Santa Casa de S?o Paulo Sao Paulo, Brazil, 01333000 Less <<
NCT00655850 - Completed - -
NCT01710592 Gastro Oesophageal Cancer Phase 2 Completed - Ireland ... More >> Mercy University Hospital Cork, Ireland Beaumont Hospital Dublin, Ireland Mater Misericordiae University hospital & Mater Private Hospital Dublin, Ireland St James's Hospital Dublin, Ireland The Adelaide and Meath Hospital Dublin, Ireland Waterford Regional Hospital Waterford, Ireland Less <<
NCT03591120 Delirium Not Applicable Recruiting March 1, 2019 United States, Illinois ... More >> Rush University Medical Center Recruiting Chicago, Illinois, United States, 60612 Contact: Robert J McCarthy, PharmD ?? 312-942-7608 ?? Robert_J_McCarthy@rush.edu ?? Contact: David H Kim, MD ?? 702-588-3470 ?? david_h_kim@rush.edu Less <<
NCT00924911 Infections, Bacterial Phase 1 Completed - United States, New York ... More >> GSK Investigational Site Buffalo, New York, United States, 14202 Less <<
NCT03710304 Cesarean Section Complications Not Applicable Recruiting June 1, 2020 Egypt ... More >> Aswan University Recruiting Aswan, Egypt, 81528 Contact: hany f sallam, md ?? 01092440504 ext 002 ?? nahla.elsayed@aswu.ed.eg Less <<
NCT02541643 - - - United States, New York ... More >> Icahn School.of Medicine at Mount Sinai New York, New York, United States, 10029 Less <<
NCT01411410 Neoplasms Phase 1 Completed - United States, Missouri ... More >> Saint Louis, Missouri, United States, 63110 United States, New York New York, New York, United States, 10065 United States, Texas Houston, Texas, United States, 77030 Less <<
NCT02360696 - Unknown July 2016 United States, Missouri ... More >> Children's Mercy Recruiting Kansas City, Missouri, United States, 64108 Contact: Nancy E. Lathrom, CCRC ?? 816-855-1860 ?? nelathrom@cmh.edu ?? Contact: Craig A. Friesen, MD ?? 816.234.3016 ?? cfriesen@cmh.edu ?? Sub-Investigator: Jennifer V. Schurman, PhD ?? ?? ?? Principal Investigator: Steven Leeder, PharmD, PhD ?? ?? ?? Principal Investigator: Craig A. Friesen, MD ?? ?? ?? Sub-Investigator: Shui Q. Ye, MD, PhD ?? ?? ?? Sub-Investigator: Nancy E. Lathrom, CCRC ?? ?? ?? Sub-Investigator: Trevor J. Cole, BS Less <<
NCT02349763 Hypersensitivity Reaction Phase 3 Unknown August 2015 Thailand ... More >> Rajavithi Hospital Bangkok, Thailand, 10400 Less <<
NCT01074437 Hemangioma Phase 2 Terminated(Insufficient enroll... More >>ment) Less << - United States, Washington ... More >> Seattle Children's Hospital Seattle, Washington, United States, 98105 Less <<
NCT01074437 - Terminated(Insufficient enroll... More >>ment) Less << - -
NCT01734759 Healthy Phase 1 Completed - United States, Minnesota ... More >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Less <<
NCT03301454 Esophageal Cancer, Squamous Ce... More >>ll Less << Phase 2 Recruiting February 2022 France ... More >> Centre Hospitalier Universitaire Not yet recruiting Amiens, France, 80080 Contact: Vincent HAUTEFEUILLE, MD ?? +33322088849 ?? heutefeuille.vincent@chu-amiens.fr ?? Principal Investigator: Vincent HAUTEFEUILLE, MD ?? ?? ?? Centre Paul Papin Not yet recruiting Angers, France, 49055 Contact: Olivier CAPITAIN, MD ?? +33240679900 ?? olivier.capitain@ico.unicancer.fr ?? Principal Investigator: Olivier CAPITAIN, MD ?? ?? ?? Sub-Investigator: Véronique GUERIN-MEYER, MD ?? ?? ?? Sub-Investigator: Julie VANBOCKSTAEL, MD ?? ?? ?? Centre Fran?ois Baclesse Not yet recruiting Caen, France, 14076 Contact: Marie-Pierre GALAIS, MD ?? +33231455016 ?? mp.galais@baclesse.fr ?? Principal Investigator: Marie-Pierre GALAIS, MD ?? ?? ?? Sub-Investigator: Fran?oise POLYCARPE-OSAER, MD ?? ?? ?? Sub-Investigator: Aurélie PARZY, MD ?? ?? ?? Sub-Investigator: Stéphane CORBINAIS, MD ?? ?? ?? Centre Oscar Lambret Recruiting Lille, France, 59020 Contact: Farid EL HAJBI, MD ?? +33320295266 ?? f-elhajbi@o-lambret.fr ?? Sub-Investigator: Frederik LAESTADIUS, MD ?? ?? ?? Sub-Investigator: Diane PANNIER, MD ?? ?? ?? Sub-Investigator: Natacha STERN, MD ?? ?? ?? Sub-Investigator: Nicolas PENEL, PhD ?? ?? ?? Sub-Investigator: Thomas RYCKEWAERT, MD ?? ?? ?? Centre René Gauducheau Not yet recruiting Nantes, France, 44805 Contact: Olivier CAPITAIN, MD ?? +33240679900 ?? olivier.capitain@ico.unicancer.fr ?? Sub-Investigator: Hélène SENELLART, MD ?? ?? ?? Sub-Investigator: Sandrine HIRET, MD ?? ?? ?? Principal Investigator: Olivier CAPITAIN, MD ?? ?? ?? Sub-Investigator: Judith RAIMBOURG, MD ?? ?? ?? Centre Armoricain de Radiothérapie, Imagerie médicale et Oncologie Not yet recruiting Plérin, France, 22190 Contact: Pierre-Luc ETIENNE, MD ?? +33296752216 ?? pl.etienne@cario-sante.fr ?? Principal Investigator: Pierre-Luc ETIENNE, MD ?? ?? ?? Sub-Investigator: Jér?me MARTIN-BABAU, MD ?? ?? ?? Sub-Investigator: Dominique BESSON, MD ?? ?? ?? Sub-Investigator: Anne-Claire HARDY-BESSARD, MD ?? ?? ?? Centre Eugène Marquis Not yet recruiting Rennes, France, 35042 Contact: Julien EDELINE, Pr ?? +33299253000 ?? j.edeline@rennes.unicancer.fr ?? Principal Investigator: Samuel LE SOURD, MD ?? ?? ?? Sub-Investigator: Anais BODERE, MD ?? ?? ?? Sub-Investigator: Julien EDELINE, PhD ?? ?? ?? Sub-Investigator: Claire LARIBLE, MD ?? ?? ?? Sub-Investigator: Fanny LE DU, MD ?? ?? ?? Sub-Investigator: Astrid LIEVRE, MD ?? ?? ?? Sub-Investigator: Marc PRACHT, MD Less <<
NCT01048229 Early-stage Parkinson's Diseas... More >>e Less << Phase 4 Terminated(recruitment) - -
NCT00551122 Brain and Central Nervous Syst... More >>em Tumors Extragonadal Germ Cell Tumor Ovarian Cancer Testicular Germ Cell Tumor Less << Phase 1 Phase 2 Unknown - United Kingdom ... More >> Queen Elizabeth Hospital at University Hospital of Birmingham NHS Trust Recruiting Birmingham, England, United Kingdom, B15 2TH Contact: Michael H. Cullen, MD ?? 0121-627-2444 ?? ?? Southampton General Hospital Recruiting Southampton, England, United Kingdom, SO16 6YD Contact: G. Mead, MD ?? 44-23-8079-8639 ?? ?? Royal Marsden - Surrey Recruiting Sutton, England, United Kingdom, SM2 5PT Contact: Robert A. Huddart, MD ?? 44-20-8661-3457 ?? robert.huddart@icr.ac.uk Less <<
NCT00855660 Pharmacology, Clinical Phase 1 Completed - Germany ... More >> K?ln, Nordrhein-Westfalen, Germany, 51147 Less <<
NCT01032655 Helicobacter Pylori Infection Phase 4 Completed - Taiwan ... More >> National Taiwan University Hospital Taipei, Taiwan, 10002 Less <<
NCT01248962 Ovarian Cancer ... More >> Fallopian Tube Cancer Peritoneal Cancer Less << Phase 2 Completed - United States, New York ... More >> Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 Less <<
NCT00885417 H. Pylori Infection Phase 4 Completed - Taiwan ... More >> National Taiwan University Hospital Taipei, Taiwan, 10002 Less <<
NCT00001910 - Completed - United States, Maryland ... More >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Less <<
NCT03241602 Decrease Post Laproscopy Shoul... More >>der and Abdominal Pain Less << Phase 4 Completed - Egypt ... More >> Faculty of medicine CAIRO UNIVERISTY Cairo, Egypt Less <<
NCT00443963 Dyspepsia Phase 4 Terminated(The Principal Inves... More >>tigator is no longer affiliated with the Study Site.) Less << - United States, District of Col... More >>umbia Washington Hospital Center 110 Irving St. NW, Washington, District of Columbia, United States, 20010 Less <<
NCT00985608 Helicobacter Pylori Infection Phase 2 Unknown September 2009 Italy ... More >> Institute of Internal Medicine - Catholic University Recruiting Rome, Italy, 00168 Contact: Giovanni Cammarota, MD ?? 0039-06-30155948 ?? gcammarota@rm.unicatt.it ?? Principal Investigator: Giovanni Cammarota, MD Less <<
NCT03644550 Mesothelioma Phase 2 Recruiting February 28, 2023 United States, Maryland ... More >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact National Cancer Institute Referral Office ?? 888-624-1937 Less <<
NCT00285688 - Unknown December 2008 Thailand ... More >> Rajavithi Hospital Recruiting Ratchathewi, Bangkok, Thailand, 10400 Contact: Piyathida Harnsomboonrana, M.D. ?? 6618423854 ?? pboontee@yahoo.com Less <<
NCT02570529 Pancreatic Ductal Adenocarcino... More >>ma Less << Phase 4 Unknown February 2018 -
NCT01866449 Glioblastoma Multiforme (GBM) ... More >>WHO Grade IV Less << Phase 2 Completed - Germany ... More >> H?matologisch onkologische Praxis Augsburg, Germany, 86150 Stiftungsklinikum Mittelrhein GmbH Koblenz, Germany, 56068 Lars Bullinger, MD Ulm, Germany, 89081 Less <<
NCT01028807 Early Feeding ... More >> Bowel Anastomosis Less << Not Applicable Completed - Mexico ... More >> Hospital Infantil de Mexico Mexico Df, DF, Mexico, 06720 Less <<
NCT01083537 Ovarian Cancer ... More >> Peritoneal Cancer Fallopian Tube Cancer Bowel Obstruction Less << Phase 1 Phase 2 Terminated(Slow accrual) - Canada, Ontario ... More >> Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Less <<
NCT03715881 Non-Arteritic Anterior Ischemi... More >>c Optic Neuropathy (NAION) Less << Phase 2 Recruiting March 1, 2019 Iran, Islamic Republic of ... More >> Ophthalmic Research Center Recruiting Tehran, Iran, Islamic Republic of Contact: Homayon Nikkhah, MD ?? 009822591616 ?? labbafi@hotmail.com Less <<
NCT00037570 Peptic Ulcer Hemorrhage Phase 2 Completed - United States, California ... More >> Los Angeles, California, United States, 90073 San Diego, California, United States, 62103-8401 United States, Ohio Cincinnati, Ohio, United States, 45267-0595 United States, Pennsylvania Philadelphia, Pennsylvania, United States, 19140 United States, Texas Houston, Texas, United States, 77030-4211 United States, Virginia Norfolk, Virginia, United States, 23507 Less <<
NCT02441894 Prostate Cancer Phase 4 Completed - Japan ... More >> Investigational Site Number 392004 Chuo-ku, Chiba, Japan Investigational Site Number 392008 Kita-gun, Japan Investigational Site Number 392007 Kobe-shi, Hyogo, Japan Investigational Site Number 392005 Nagakute-shi, Aichi, Japan Investigational Site Number 392006 Osaka Sayama-shi, Osaka, Japan Investigational Site Number 392001 Shinjuku-ku, Tokyo, Japan Investigational Site Number 392002 Yokohama-shi, Kanagawa, Japan Investigational Site Number 392009 Yokohama-shi, Japan Less <<
NCT00199342 Stage IV Melanoma Phase 1 Phase 2 Terminated(Occurrence of 2 dos... More >>e-limiting toxicities at the initial dose level (60 mg/m2) in Part I.) Less << - United States, Alabama ... More >> Comprehensive Cancer Center- University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, Florida H. Lee Moffitt Cancer Center Tampa, Florida, United States, 22612 Less <<
NCT02555852 - Completed - Canada, Quebec ... More >> Lady Davis Institute for Medical Research, Jewish General Hospital Montreal, Quebec, Canada, H3T1E2 Less <<
NCT00247715 Dyspepsia Gas... More >>trointestinal Diseases Less << Not Applicable Completed - Netherlands ... More >> Radboud University Nijmegen Medical Center Nijmegen, Gelderland, Netherlands, 6500 HB Maastricht University Maastricht, Limburg, Netherlands, 6200 MB UMC Utrecht Utrecht, Netherlands Less <<
NCT02169856 Postoperative Nausea and Vomit... More >>ing Less << Not Applicable Completed - Pakistan ... More >> Benazir Bhutto Hospital Rawalpindi. Rawalpindi, Punjab, Pakistan, 46000 Less <<
NCT00930670 Coronary Artery Disease Phase 4 Completed - Canada, Quebec ... More >> Institut Universitaire de Cardiologie et de Pneumologie de Quebec Quebec City, Quebec, Canada, G1V4G5 Less <<
NCT03619408 - Not yet recruiting July 2020 -
NCT02441673 Post Anaesthetic Shivering Phase 2 Not yet recruiting June 2019 -
NCT01209455 Poisoning Not Applicable Unknown September 2012 United Kingdom ... More >> Clinical Research Facility, Royal Infirmary of Edinburgh Recruiting Edinburgh, Midlothian, United Kingdom, EH16 4SA Principal Investigator: Euan A Sandilands, MRCP BSc Less <<
NCT00220909 Patients Undergoing Elective C... More >>oronary Artery Bypass Graft Less << Phase 4 Terminated(Recruitment slow) - United States, Pennsylvania ... More >> Temple University School of Medicine Philadelphia, Pennsylvania, United States, 19140 Less <<
NCT02999633 T-cell Type Acute Leukemia-Pre... More >>cursor T-lymphoblastic Lymphoma/Leukaemia Less << Phase 2 Terminated(Due to an unsatisfa... More >>ctory benefit/risk ratio, as specified in & 14.8.1 of the protocol, Sanofi decided to stop enrollment and terminate ACT14596 prematurely) Less << - United States, Georgia ... More >> Investigational Site Number 8400002 Atlanta, Georgia, United States, 30342 United States, New Jersey Investigational Site Number 8400003 Hackensack, New Jersey, United States, 07601 United States, Texas Investigational Site Number 8400001 Houston, Texas, United States, 77030 Finland Investigational Site Number 2460001 Helsinki, Finland, 00029 France Investigational Site Number 2500005 Nantes Cedex 01, France, 44093 Investigational Site Number 2500001 Paris Cedex 10, France, 75475 Investigational Site Number 2500004 Pessac, France, 33600 Investigational Site Number 2500002 Pierre Benite, France, 69310 Hungary Investigational Site Number 3480001 Budapest, Hungary, 1083 Investigational Site Number 3480003 Budapest, Hungary, 1097 Investigational Site Number 3480002 Debrecen, Hungary, 4032 Italy Investigational Site Number 3800001 Bergamo, Italy, 24127 Investigational Site Number 3800004 Brescia, Italy, 25123 Lithuania Investigational Site Number 4400001 Vilnius, Lithuania, 08661 Russian Federation Investigational Site Number 6430003 Moscow, Russian Federation, 117198 Investigational Site Number 6430004 Moscow, Russian Federation, 125167 Investigational Site Number 6430001 Moscow, Russian Federation, 129301 Less <<
NCT01274130 Healthy Adult Not Applicable Completed - Korea, Republic of ... More >> Severance Hospital Seoul, Korea, Republic of, 120-752 Less <<
NCT02966665 Chronic Obstructive Pulmonary ... More >>Disease Pulmonary Artery Hypertension Heart Failure Hypertension Less << Phase 1 Recruiting August 2020 United States, Utah ... More >> George E Wahlen VA Medical Center Recruiting Salt Lake City, Utah, United States, 84132 Contact: Russell Richardson, Ph.D. ?? 801-582-1565 ?? r.richardson@hsc.utah.edu ?? Contact: Ashley Nelson, MD ?? 801-582-1565 ext 4127 ?? ash.nelson@hsc.utah.edu Less <<
NCT02123498 Eustachian Tube Dysfunction ... More >> Laryngopharyngeal Reflux Less << Phase 4 Withdrawn(IRB not approved) - United States, California ... More >> 11234 Anderson Street Loma Linda, California, United States, 92354 1895 Orange Tree Lane, Suite 102 Redlands, California, United States, 92374 Less <<
NCT00223691 Autonomic Failure ... More >> Orthostatic Hypotension Less << Phase 1 Completed - United States, Tennessee ... More >> Vanderbilt University Nashville, Tennessee, United States, 37232 Less <<
NCT02004197 Helicobacter Pylori [H. Pylori... More >>] as the Cause of Diseases Less << Phase 2 Phase 3 Completed - Pakistan ... More >> clinical trial was conducted in high risk areas of Pakistan such as Karachi, Bahawalpur, Islamabad and Rawalpindi at Shifa-Ul-Mulk Memorial Hospital, Hamdrad University Karachi, Bahawalpur Victoria Hospital and Nawaz Salik Hospital respectively Karachi, Pakistan Shifa Ul MUlk Memorial Hospital Karachi, Pakistan Less <<
NCT00131248 Gastroesophageal Reflux Phase 3 Completed - United States, Texas ... More >> Memorial Hermann Children's Hospital Houston, Texas, United States, 77030 Less <<
NCT01261546 Parapneumonic Pleural Effusion... More >> Empyema Less << Phase 2 Completed - Spain ... More >> Hospital Carlos Haya Malaga, Andalucia, Spain Complejo Hospitalario Toledo Toledo, Castilla La Mancha, Spain Hospital Principe de Asturias Alcalá de Henares, Madrid, Spain Hospital Universitario de Getafe Getafe, Madrid, Spain Hospital Infanta Sofia San Sebastián de los Reyes, Madrid, Spain, 28014 Hospital Infantil La Paz Madrid, Spain, 28037 Hospital Ramón y Cajal Madrid, Spain Hospital Universitario Gregorio Mara?ón Madrid, Spain Less <<
NCT02258815 Neuroblastoma Recurrent Phase 2 Unknown December 2015 Austria ... More >> University Hospital Graz Recruiting Graz, Austria, 8036 Contact: Wolfgang Schwinger, MD, PhD ?? +43 31638512605 ?? wolfgang.schwinger@medunigraz.at ?? Principal Investigator: Wolfgang Schwinger, MD, PhD ?? ?? ?? St. Anna Childrens Hospital Recruiting Vienna, Austria, 1090 Contact: Ruth Ladenstein, MD, PhD ?? 43 1 40470 3250 ?? ruth.ladenstein@ccri.at ?? Principal Investigator: Ruth Ladenstein, MD, PhD ?? ?? ?? Germany University Hospital Greifswald Recruiting Greifswald, Germany, 17475 Contact: Holger Lode, MD, PhD ?? +49 3834866301 ?? lode@uni-greifswald.de ?? Principal Investigator: Holger Lode, MD, PhD ?? ?? ?? University Hospital Tuebingen Recruiting Tuebingen, Germany, 72076 Contact: Peter Lang, MD, PhD ?? +4970712983781 ?? peter.lang@med.uni-tuebingen.de ?? Principal Investigator: Peter Lang, MD, PhD Less <<
NCT00161200 Esophageal Metaplasia Phase 3 Terminated(slow accrual) - United States, New Jersey ... More >> Cancer Institute of New Jersey New Brunswick, New Jersey, United States, 08901 Less <<
NCT01332630 Breast Cancer Phase 2 Completed - United States, Texas ... More >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT01332630 - Completed - -
NCT00131248 - Completed - -
NCT02703896 Pulmonary Aspiration of Gastri... More >>c Contents Less << Phase 4 Completed - -
NCT00030992 - Completed - -
NCT00030992 Renal Cell Carcinoma Phase 2 Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT03667703 Congenital Heart Disease ... More >> Upper Gastrointestinal Bleeding Stress Ulcer Infection Less << Not Applicable Not yet recruiting June 30, 2021 United States, Massachusetts ... More >> Boston Children's Hospital Not yet recruiting Boston, Massachusetts, United States, 02115 Contact: Kimberly I Mills, MD ?? 617-355-7866 ?? kimberly.mills@cardio.chboston.org ?? Contact: Ben D Albert, MD ?? 617-355-7866 ?? ben.albert@childrens.harvard.edu Less <<
NCT03583567 Protamine Adverse Reaction Phase 4 Recruiting December 1, 2020 Thailand ... More >> Siriraj Hospital Recruiting Bangkok, Thailand, 10700 Contact: Sirilak Suksompoong, MD ?? ?? ssuksompong5@gmail.com Less <<
NCT03468777 Healthy Phase 1 Terminated(The study has been ... More >>terminated due to pending data analysis) Less << - Belgium ... More >> Clinical Pharmacology Unit Merksem, Belgium, 2170 Less <<
NCT00585351 - Completed - -
NCT00585351 Stroke Not Applicable Completed - United States, Iowa ... More >> University of Iowa Iowa City, Iowa, United States, 52242 Less <<
NCT00590928 Critically Ill Patients ... More >> Indication for Stress Ulcer Prophylaxis Less << Phase 4 Completed - Austria ... More >> Medical University of Vienna, Department of Medicine III, ICU Vienna, Austria, 1090 Less <<
NCT00000964 HIV Infections Phase 1 Completed - United States, Maryland ... More >> Johns Hopkins Adult AIDS CRS Baltimore, Maryland, United States, 21205 Less <<
NCT00405119 Gastroesophageal Reflux Diseas... More >>e Reflux, Gastroesophageal Less << Phase 2 Completed - Australia, New South Wales ... More >> GSK Investigational Site Randwick, New South Wales, Australia, 2031 Australia, Queensland GSK Investigational Site Herston, Queensland, Australia, 4006 Less <<
NCT03140033 Hemorrhage Postpartum Phase 2 Recruiting May 2017 Egypt ... More >> Ain shams maternity hospital Recruiting Cairo, Egypt Contact: Mohamed Fathy, M.B.B.Ch ?? 00201099984100 ?? Mohamedfathy31085@gmail.com ?? Contact: AMR Helmy, MD.MRCOG ?? 00201227900014 ?? am_helmy77@hotmail.com Less <<
NCT03011463 Pharmacokinetics ... More >> Inhibition Enzyme Drug Interaction Potentiation Less << Phase 1 Completed - -
NCT00702871 Ventilator Associated Pneumoni... More >>a Etiological Organisms Antimicrobial Drug Susceptibility Pattern Stress Ulcer Prophylaxis Less << Phase 4 Completed - India ... More >> Maulana Azad Medical College and Lok Nayak Hospital Delhi, India, 110002 Less <<
NCT01976078 - Completed - United States, California ... More >> Children's Hospital Los Angeles Los Angeles, California, United States, 90027 Less <<
NCT00668317 - Terminated(Primary care physic... More >>ians began prescribing antacid therapy for chronic cough) Less << - -
NCT00668317 Cough Phase 3 Terminated(Primary care physic... More >>ians began prescribing antacid therapy for chronic cough) Less << - United Kingdom ... More >> Clinical Trials Unit , Cardiovascular and respiratory studies, Castle Hill Hospital Cottingham, East Yorkshire, United Kingdom, HU16 5JQ Less <<
NCT02172417 Healthy Phase 1 Completed - -
NCT00633412 NSAID Associated Gastric Ulcer... More >>s Less << Phase 3 Completed - -
NCT00839306 Gastroesophageal Reflux Diseas... More >>e (GERD) Less << Phase 3 Completed - United States, Illinois ... More >> Associates, Ltd. Moline, Illinois, United States, 61265 Midwest Clinical Moline, Illinois, United States, 61265 Research Moline, Illinois, United States, 61265 Moline, Illinois, United States, 61265 Less <<
NCT02733640 Antiplatelet Effect Not Applicable Completed - Korea, Republic of ... More >> Seoul National University Bundang Hospital Seongnam, Gyeonggi-do, Korea, Republic of, 463-707 Less <<
NCT00838526 Gastroesophageal Reflux Diseas... More >>e (GERD) Less << Phase 3 Completed - United States, Illinois ... More >> Ltd. Moline, Illinois, United States, 61265 Midwest Clinical Moline, Illinois, United States, 61265 Research Associates Moline, Illinois, United States, 61265 Moline, Illinois, United States, 61265 Less <<
NCT00839306 - Completed - -
NCT00838526 - Completed - -
NCT01908257 Healthy Phase 1 Completed - United States, California ... More >> Cypress, California, United States, 90630 Less <<
NCT01392755 Healthy Volunteer Phase 1 Completed - United States, Kansas ... More >> Lenexa, Kansas, United States, 66219 Less <<
NCT01538797 Reflux Oesophagitis Phase 1 Completed - United Kingdom ... More >> Hammersmith Medicines Research London, United Kingdom, NW10 7EW Less <<
NCT00401752 Gastric Ulcer Phase 3 Completed - China, Fujian ... More >> Research Site Fuzhou, Fujian, China China, Guangdong Research Site Guangzhou, Guangdong, China China, Hubei Research Site Wuhan, Hubei, China China, Jiangsu Research Site Suzhou, Jiangsu, China China, Liaoning Research Site Shenyang, Liaoning, China China, Shanxi Research Site Xi'an, Shanxi, China China Research Site Beijing, China Research Site Shanghai, China Hong Kong Research Site Hong Kong, Hong Kong Less <<
NCT00633672 NSAID Associated Gastric Ulcer... More >>s Less << Phase 3 Completed - -
NCT03145012 Cancer Phase 4 Not yet recruiting April 30, 2019 Canada, Nova Scotia ... More >> Nova Scotia Health Authority Not yet recruiting Halifax, Nova Scotia, Canada, B3H 1V7 Contact: Lisa Barrett, MD ?? ?? lisa.barrett@nshealth.ca ?? Contact: Jill Moore ?? ?? jill.moore@nshealth.ca Less <<
NCT02170792 Healthy Phase 1 Completed - -
NCT01682408 Pharmacokinetics Phase 1 Completed - United States, Kansas ... More >> Overland Park, Kansas, United States Less <<
NCT00401752 - Completed - -
NCT01737840 Dyspepsia Phase 4 Completed - Turkey ... More >> Akdeniz University Antalya, Turkey, 07050 Less <<
NCT00002106 HIV Infections PHASE2 COMPLETED - Pacific Oaks Med Group, Sherma... More >>n Oaks, California, 91403, United States|Community Research Initiative, Coral Gables, Florida, 33146, United States|Duke Univ Med Ctr, Durham, North Carolina, 27710, United States|Houston Clinical Research Network, Houston, Texas, 77006, United States Less <<
NCT01539655 Medullary Thyroid Cancer Phase 1 Completed - United States, Kansas ... More >> Research Site Overland Park, Kansas, United States Less <<
NCT00527878 JOB's Syndrome ... More >> Hyper-IgE Recurrent Infection Syndrome Immune Deficiency Less << Phase 2 Terminated(Failure to enroll a... More >>dequate patient numbers due to small number of eligible patients) Less << - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT00527878 - Terminated(Failure to enroll a... More >>dequate patient numbers due to small number of eligible patients) Less << - -
NCT01896557 Coronary Artery Disease ... More >> Drug Interaction Potentiation Less << Phase 4 Completed - -
NCT02700087 Laryngomalacia ... More >> Acid Reflux Stridor Less << Not Applicable Withdrawn February 2017 United States, California ... More >> Lucile Packard Children's Hospital Stanford Palo Alto, California, United States, 94304 Less <<
NCT02197143 Dyspepsia Phase 4 Completed - Turkey ... More >> Pamukkale Universty Denizli, Turkey, 20000 Less <<
NCT00247130 Peptic Ulcers Phase 4 Withdrawn(Superiority of iv om... More >>eprazole to ranitidine has already been proven by others.) Less << - Japan ... More >> Department of Internal Medicine, Keio University School of Medicine Tokyo, Japan, 1608582 Less <<
NCT01131702 Healthy Phase 1 Completed - Canada, Quebec ... More >> Anapharm Inc. Montreal, Quebec, Canada, G1V 2K8 Less <<
NCT02195804 Healthy Phase 1 Completed - -
NCT01737840 - Completed - -
NCT01896557 - Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.85mL

0.57mL

0.29mL

14.25mL

2.85mL

1.43mL

28.50mL

5.70mL

2.85mL

References

 

Historical Records

Categories