成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 655-86-7 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 655-86-7
Chemical Structure| 655-86-7
Structure of 655-86-7 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 655-86-7 ]

Related Doc. of [ 655-86-7 ]

Alternatived Products of [ 655-86-7 ]
Product Citations

Product Details of [ 655-86-7 ]

CAS No. :655-86-7 MDL No. :MFCD00160693
Formula : C12H10N4 Boiling Point : -
Linear Structure Formula :C12H6N2(NH2)2 InChI Key :VZPGINJWPPHRLS-UHFFFAOYSA-N
M.W : 210.23 Pubchem ID :410099
Synonyms :
Chemical Name :Phenazine-2,3-diamine

Calculated chemistry of [ 655-86-7 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 16
Num. arom. heavy atoms : 14
Fraction Csp3 : 0.0
Num. rotatable bonds : 0
Num. H-bond acceptors : 2.0
Num. H-bond donors : 2.0
Molar Refractivity : 65.85
TPSA : 77.82 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : No
P-gp substrate : Yes
CYP1A2 inhibitor : Yes
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : Yes
CYP3A4 inhibitor : Yes
Log Kp (skin permeation) : -6.68 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.34
Log Po/w (XLOGP3) : 1.27
Log Po/w (WLOGP) : 1.96
Log Po/w (MLOGP) : 1.21
Log Po/w (SILICOS-IT) : 1.47
Consensus Log Po/w : 1.45

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -2.59
Solubility : 0.539 mg/ml ; 0.00256 mol/l
Class : Soluble
Log S (Ali) : -2.5
Solubility : 0.66 mg/ml ; 0.00314 mol/l
Class : Soluble
Log S (SILICOS-IT) : -4.29
Solubility : 0.0107 mg/ml ; 0.0000511 mol/l
Class : Moderately soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 2.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.7

Safety of [ 655-86-7 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 655-86-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 655-86-7 ]

[ 655-86-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 652-12-0 ]
  • [ 655-86-7 ]
  • [ 1431328-08-3 ]
YieldReaction ConditionsOperation in experiment
19% With zinc diacetate; at 220℃; for 12h;Inert atmosphere; 2,3-Phenazinediamine(1.06g, 5.05 mmol) , zinc acetate(1.85g, 10.08mmol) and 3,4,5,6-Tetrafluorophthalic anhydride (1.21g 5.49 mmol) were well mixed by a mortar, then heated at 220 ℃ in a glass tube protected under argon atmosphere for 12 hours. After that the mixture was cooled down and washed by tetrahydrofuran (THF). The eluted solution was condensed and purified through column chromatography with ethyl acetate and hexane (1:1) to afford compound 1 as orange colour powder, (341mg, yield 19%. 1H NMR (300 MHz, DMSO-d6, 298 K): δ= 7.882 (m, 2H), 8.205 (m, 3H), 8.450 (s, 2H), 13.224 (s, 1H). FTIR (KBr), 3469, 3059, 3038, 2337, 1542, 1525, 1510, 1489, 1474, 1419, 1369, 1350, 1308, 1273, 1219, 1206, 1184, 1171, 1136, 1085, 1036, 964, 899, 890, 833, 762cm-1. MALDI-TOF MS: Calc. for C19H8F4N4: [M] 368.0685, Found: [M] 368.5. HR-MS calcd for C19H8F4N4 [M+1], 369.1685; found, 369.0754.
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 655-86-7 ]

Amines

Chemical Structure| 581-28-2

[ 581-28-2 ]

Acridin-2-amine

Similarity: 0.74

Chemical Structure| 132833-03-5

[ 132833-03-5 ]

Isoquinolin-3-ylmethanamine

Similarity: 0.74

Chemical Structure| 1628557-04-9

[ 1628557-04-9 ]

Isoquinolin-3-ylmethanamine hydrochloride

Similarity: 0.74

Chemical Structure| 90-45-9

[ 90-45-9 ]

9-Aminoacridine

Similarity: 0.73

Chemical Structure| 98555-00-1

[ 98555-00-1 ]

7-Aminoquinoxalin-2(1H)-one

Similarity: 0.73

Related Parent Nucleus of
[ 655-86-7 ]

Other Aromatic Heterocycles

Chemical Structure| 92-82-0

[ 92-82-0 ]

Phenazine

Similarity: 0.96

Chemical Structure| 536753-86-3

[ 536753-86-3 ]

2-Methyldibenzo[f,h]quinoxaline

Similarity: 0.82

Chemical Structure| 581-28-2

[ 581-28-2 ]

Acridin-2-amine

Similarity: 0.74

Chemical Structure| 90-45-9

[ 90-45-9 ]

9-Aminoacridine

Similarity: 0.73

Chemical Structure| 611-64-3

[ 611-64-3 ]

9-Methylacridine

Similarity: 0.71

; ;