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Chemical Structure| 63074-08-8 Chemical Structure| 63074-08-8
Chemical Structure| 63074-08-8

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CAS No.: 63074-08-8

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Terazosin HCl is a selective antagonist for alpha-adrenergic receptor, used for treatment for hypertension and prostate enlargement (BPH) through lowering the blood pressure with elimination half-life of ?12 hours.

Synonyms: Terazosin (hydrochloride); Hytrin; A-45975

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Product Details of Terazosin HCl

CAS No. :63074-08-8
Formula : C19H26ClN5O4
M.W : 423.89
SMILES Code : O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4OCCC4.[H]Cl
Synonyms :
Terazosin (hydrochloride); Hytrin; A-45975
MDL No. :MFCD00467965
InChI Key :IWSWDOUXSCRCKW-UHFFFAOYSA-N
Pubchem ID :44383

Safety of Terazosin HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Related Pathways of Terazosin HCl

GPCR

Isoform Comparison

Biological Activity

Target
  • α-adrenergic receptor

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00000620 Atherosclerosis ... More >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Less << Phase 3 Completed - United States, Minnesota ... More >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Less <<
NCT03339258 Stress Disorders, Post-Traumat... More >>ic Less << Phase 2 Recruiting June 2021 United States, California ... More >> San Francisco VA Medical Center Recruiting San Francisco, California, United States, 94121 Contact: Andrew Levihn-Coon, B.A. ?? 415-221-4810 ext 23809 ?? andrew.levihn-coon@va.gov Less <<
NCT01323998 - Completed - -
NCT00000620 - Completed - -
NCT00684489 Hypertension Not Applicable Completed - -
NCT01323998 - Completed - -
NCT01332487 - Completed - -
NCT01332487 - Completed - -
NCT03653845 Primary Aldosteronism ... More >> Hypertension Less << Phase 3 Recruiting January 1, 2020 China, Chongqing ... More >> The third hospital affiliated to the Third Military Medical University Recruiting Chongqing, Chongqing, China, 400042 Contact: Hongbo He, MD. ?? 86-23-68757880 ?? cqhehongbo@gmail.com ?? Principal Investigator: Zhiming Zhu, MD. ?? ?? ?? China The third hospital affiliated to the Third Military Medical University Recruiting Chongqing, China, 400042 Contact: Zhiming Zhu, MD, PhD ?? 86-023-68705094 ?? zhuzm@yahoo.com ?? Principal Investigator: Zhiming Zhu, MD, PhD Less <<
NCT01386983 - Completed - -
NCT01332435 - Completed - -
NCT01218243 Benign Prostatic Hyperplasia (... More >>BPH) Less << Phase 2 Completed - China ... More >> Guang'an Men Hospotal Affiliated to China Academy of Chinese Medical Sciences Beijing, China, 100053 Less <<
NCT01390870 - Completed - -
NCT01332435 - Completed - -
NCT02966717 Renal Insufficiency, Chronic ... More >> Nephrotic Syndrome Less << Phase 2 Active, not recruiting October 2021 China, Guangdong ... More >> Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China, 510282 Less <<
NCT01390870 - Completed - -
NCT01218243 - Completed - -
NCT01386983 - Completed - -
NCT01435954 - Completed - -
NCT00438113 Atrial Fibrillation Phase 4 Completed - Canada, Nova Scotia ... More >> QE II Health Sciences Centre Halifax, Nova Scotia, Canada, B3H 3A7 Less <<
NCT02244333 - Completed - -
NCT00700583 Nocturia Not Applicable Completed - Korea, Republic of ... More >> Department of Urology, Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Less <<
NCT02046395 Type 2 Diabetes ... More >> Hypertension Less << Phase 4 Recruiting December 2019 United States, Louisiana ... More >> Tulane University Health Sciences Center Recruiting New Orleans, Louisiana, United States, 70112 Contact: Bonnie L Katalenich, MPH ?? 504-988-0200 ?? bkatalen@tulane.edu ?? Principal Investigator: Tina Thethi, MD, MPH Less <<
NCT01508637 Cardiovascular Effects Not Applicable Unknown December 2015 United States, Washington ... More >> University of Washington Medical Center Recruiting Seattle, Washington, United States, 98195 Less <<
NCT00687388 Benign Prostatic Hyperplasia Phase 4 Withdrawn(in order to prepare ... More >>a new clinical trial to evaluate with pathological change) Less << - Korea, Republic of ... More >> Severance Hospital Seoul, Korea, Republic of, 120-752 Samsung Medical Center Seoul, Korea, Republic of, 135-710 Asan Medical Center Seoul, Korea, Republic of, 138-736 Less <<
NCT00693199 Lower Urinary Tract Symptoms ... More >> Hypertension Less << Not Applicable Completed - China, Anhui ... More >> Biomedicine Inistitute of Anhui Medical University Hefei, Anhui, China, 230032 Less <<
NCT01530243 Disorder of Urinary Stent Phase 2 Phase 3 Completed - Iran, Islamic Republic of ... More >> Imam Khomeini Hospital Urmia, Azerbaijan-gharbi, Iran, Islamic Republic of Less <<
NCT00563485 Prostatic Hyperplasia ... More >> Urinary Retention Less << Not Applicable Terminated - China ... More >> Prince of Wales Hospital Hong Kong, China Less <<
NCT01366664 Ejaculation Phase 1 Completed - United States, Alabama ... More >> Anniston, Alabama, United States United States, Arizona Tempe, Arizona, United States United States, California Costa Mesa, California, United States United States, Florida Miramar, Florida, United States United States, Tennessee Knoxville, Tennessee, United States United States, Texas Dallas, Texas, United States Less <<
NCT03195673 Carotid Artery Stenosis Phase 2 Recruiting December 15, 2019 China, Beijing ... More >> Beijing Anzhen Hospital Recruiting Beijing, Beijing, China, 100029 Contact: He Yin, MD ?? ?? ?? The Luhe Teaching Hospital of the Capital Medical University Recruiting Beijing, Beijing, China, 101100 Contact: Xiaokun Geng, MD Less <<
NCT02244255 Prostatic Hyperplasia Phase 4 Completed - -
NCT00237510 Antidepressant Induced Excessi... More >>ve Sweating Less << Not Applicable Completed - United States, Pennsylvania ... More >> Thomas Jefferson University Department of Psychiatry and Human Behavior Philadelphia, Pennsylvania, United States, 19107 Less <<
NCT00449683 Hyperhidrosis Phase 4 Completed - United States, Pennsylvania ... More >> Thomas Jefferson University, Department of Psychiatry Philadelphia, Pennsylvania, United States, 19107 Less <<
NCT01530243 - Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.36mL

0.47mL

0.24mL

11.80mL

2.36mL

1.18mL

23.59mL

4.72mL

2.36mL

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