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[ CAS No. 616-83-1 ] {[proInfo.proName]}

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Chemical Structure| 616-83-1
Chemical Structure| 616-83-1
Structure of 616-83-1 * Storage: {[proInfo.prStorage]}

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Product Details of [ 616-83-1 ]

CAS No. :616-83-1 MDL No. :MFCD00129811
Formula : C7H6ClNO4S Boiling Point : No data available
Linear Structure Formula :- InChI Key :OQFYBGANSUNUAO-UHFFFAOYSA-N
M.W : 235.64 Pubchem ID :560638
Synonyms :

Safety of [ 616-83-1 ]

Signal Word:Danger Class:8
Precautionary Statements:P280-P305+P351+P338-P310 UN#:3265
Hazard Statements:H314 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 616-83-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 616-83-1 ]

[ 616-83-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 616-83-1 ]
  • [ 932-32-1 ]
  • [ 1303573-46-7 ]
YieldReaction ConditionsOperation in experiment
47% With pyridine; dmap; In dichloromethane; at 0 - 20℃; General procedure: To a solution of the appropriate aniline in dry CH2Cl2 (10 mL for 3 mmol of aniline), pyridine (1.5 eq) and catalytic DMAP (15 mg) were added, then the resulting mixture was cooled to 0 C. Subsequently, commercially available sulfonylchloride 6 (1.2 eq) in dry CH2Cl2 (10 mL for 3.6 mmol of benzenesulfonylchloride) was added dropwise and the reaction was kept under stirring at RT overnight. The reaction mixture was acidified with 1N aqueous HCl, extracted several times with CH2Cl2 and the combined organic phase was dried over anhydrous sodium sulphate. Evaporation under vacuum of the organic solvent afforded a crude product which was purified by column chromatography over silica gel, to yield the sulfonamidic derivative.
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