Structure of 615-55-4
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Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 615-55-4 |
Formula : | C6H5Br2N |
M.W : | 250.92 |
SMILES Code : | NC1=CC=C(Br)C(Br)=C1 |
MDL No. : | MFCD00041310 |
Boiling Point : | No data available |
InChI Key : | QFTJOYLPELHHCO-UHFFFAOYSA-N |
Pubchem ID : | 521981 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302-H312-H332 |
Precautionary Statements: | P280 |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
78% | With tetrabutylammomium bromide; copper(ll) bromide; In ethanol; at 25℃; | General procedure: A round bottom flask was charged with Bu4NBr (2 mmol, 0.64 g), EtOH (8 mL) and 2-methylaniline (2 mmol, 0.21 g) followed by CuBr2 (3 mmol, 0.67 g). The resulted mixture was stirred at 25 C. After the completion of the reaction (monitored by TLC), the solvent was evaporated under reduced pressure. To the residue was added ammonium hydroxide (5 mL, 25% w/v) and water (5 mL) with stirring, and the suspension was extracted with DCM(10 mL×4) The organic phase was washed with saturated brine and dried over anhydrous Na2SO4. The product 2b was obtained using flash chromatograph column eluted with PE : EA (5 : 1). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
Following the procedure of Example 3 the following substituted anilines: 3,4-dibromoaniline 3,4-difluoroaniline 3-chloro-4-bromoaniline |