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Chemical Structure| 611-99-4 Chemical Structure| 611-99-4
Chemical Structure| 611-99-4

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CAS No.: 611-99-4

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Product Details of 4,4'-Dihydroxybenzophenone

CAS No. :611-99-4
Formula : C13H10O3
M.W : 214.22
SMILES Code : C2=C(C(C1=CC=C(O)C=C1)=O)C=CC(=C2)O
MDL No. :MFCD00002358
InChI Key :RXNYJUSEXLAVNQ-UHFFFAOYSA-N
Pubchem ID :69150

Safety of 4,4'-Dihydroxybenzophenone

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 4,4'-Dihydroxybenzophenone

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 611-99-4 ]
  • Downstream synthetic route of [ 611-99-4 ]

[ 611-99-4 ] Synthesis Path-Upstream   1~2

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  • [ 611-99-4 ]
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YieldReaction ConditionsOperation in experiment
91.1% With ammonia In water EXAMPLE 5
Preparation of 4-amino-5-chloro-1-phenylpyridazin-6-one (chloridazon) using 4,4'-dihydroxybenzophenone as catalyst
In a 250 ml stirring autoclave, 100 parts of water, 70 parts (1.03 mol) of 25percent strength ammonia, 12 parts (0.05 mol) of 4,5-dichloro-1-phenylpyridazin-6-one (purity: 99.7percent) and 10.7 parts (0.05 mol) of 4,4'-dihydroxybenzophenone were stirred at 130° C. for 8 hours.
The pressure rose steadily to about 4.5 bar.
After stirring overnight, the autoclave was depressurized to atmospheric pressure, with the excess ammonia being stripped off.
After cooling to room temperature, the precipitated solid was filtered off, washed with water and dried at 50° C. in a vacuum drying oven.
This gave 10.2 parts of 4-amino-5-chloro-1-phenylpyridazin-6-one having a purity of 98.9percent; this corresponds to a yield of 91.1percent of theory.
The pH of the filtrate was adjusted to 1.5 using 60percent strength sulfuric acid and the precipitated 4,4'-dihydroxybenzophenone was filtered off, washed with water and dried.
This gave 10.9 parts of 4,4'-dihydroxybenzophenone having a purity of 98.3percent; this corresponds to 100percent of the amount of catalyst used.
References: [1] Patent: US6538135, 2003, B1, .
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  • [ 1698-60-8 ]
References: [1] Patent: US6538135, 2003, B1, .
 

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