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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 59804-37-4 Chemical Structure| 59804-37-4
Chemical Structure| 59804-37-4

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CAS No.: 59804-37-4

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Tenoxicam is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

Synonyms: Ro-12-0068

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of [ 59804-37-4 ]

CAS No. :59804-37-4
Formula : C13H11N3O4S2
M.W : 337.37
SMILES Code : O=C(C1=C(O)C2=C(C=CS2)S(N1C)(=O)=O)NC3=NC=CC=C3
Synonyms :
Ro-12-0068
MDL No. :MFCD00083502
InChI Key :LZNWYQJJBLGYLT-UHFFFAOYSA-N
Pubchem ID :54677971

Safety of [ 59804-37-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:Ⅲ

Application In Synthesis [ 59804-37-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 59804-37-4 ]

[ 59804-37-4 ] Synthesis Path-Downstream   1~26

  • 1
  • [ 504-29-0 ]
  • [ 59804-25-0 ]
  • [ 59804-37-4 ]
YieldReaction ConditionsOperation in experiment
76.9% In 5,5-dimethyl-1,3-cyclohexadiene; for 6h;Reflux; 5.4 g of TNXK-3, 300 ml xylene and 1.4g 2-aminopyridine in xylene solution 2.8 ml heating to reflux. After stirring reaction 6 hours, cooling. the majority of the solvent is removed under reduced pressure, cooling, filtering, the filter cake by adding 15 ml in water, adding sodium hydroxide 1 g and methanol 55 ml, heating the solvent, used to decolorize with active carbon, the filtrate is adjusted to PH hydrochloric acid 3, is cooled and is filtered, the filter cake is benzodioxane recrystallized, to get the yellow solid 4.2 g, yield 76.9%.
EXAMPLE 9 By reacting 2-pyridylamine with 3-carbomethoxy-4-hydroxy-2-methylthieno[2,3-e]-1,2-thiazine 1,1-dioxide for 7 hours in a manner analogous to that described in Example 1, there is obtained 4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide of decomposition point 209-213 C (recrystallization from xylene).
  • 2
  • [ 59804-37-4 ]
  • [ 504-29-0 ]
  • 3
  • [ 59804-37-4 ]
  • [ 504-29-0 ]
  • 4-hydroxy-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide [ No CAS ]
  • 2-Methylamino-3-oxo-3-(3-sulfo-thiophen-2-yl)-propionic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
Examples of the compounds of Formula I are: 4-hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide (piroxicam), 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl) 2H-1,2-benzo-thiazine-3-carboxamide-1,1-dioxide (isoxicam), 4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno [2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide (tenoxicam), and 4-hydroxy-2-methyl-N-(2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide (sudoxicam).
  • 6
  • [ 527-69-5 ]
  • [ 59804-37-4 ]
  • 2-methyl-1,1-dioxido-3-[(pyridin-2-ylamino)carbonyl]-2H-thieno[2,3-e][1,2]thiazin-4-yl 2-furoate hydrochloride [ No CAS ]
  • 7
  • [ 102-92-1 ]
  • [ 59804-37-4 ]
  • 2-methyl-1,1-dioxido-3-[(pyridin-2-ylamino)carbonyl]-2H-thieno[2,3-e][1,2]thiazin-4-yl 3-phenylprop-2-enoate hydrochloride [ No CAS ]
  • 8
  • [ 98-88-4 ]
  • [ 59804-37-4 ]
  • 2-methyl-1,1-dioxido-3-[(pyridin-2-ylamino)carbonyl]-2H-thieno[2,3-e][1,2]thiazin-4-yl benzoate hydrochloride [ No CAS ]
  • 9
  • [ 59804-37-4 ]
  • [ 75-36-5 ]
  • 2-methyl-1,1-dioxido-3-[(pyridin-2-ylamino)carbonyl]-2H-thieno[2,3-e][1,2]thiazin-4-yl acetate hydrochloride [ No CAS ]
  • 10
  • [ 59804-37-4 ]
  • [ 74-88-4 ]
  • 4-methoxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide [ No CAS ]
  • [ 868522-78-5 ]
  • 11
  • [ 59804-37-4 ]
  • 5-methyl-5H,6H-pyrido[2',1':2,3]pyrimido[5,4-c]thieno[2,3-e][1,2]thiazin-6-one 4,4-dioxide [ No CAS ]
  • 12
  • [ 59804-37-4 ]
  • 4-methyl-1-phenyl-1,4-dihydropyrazolo[4,3-c]thieno[2,3-e][1,2]thiazin-3(2H)-one 5,5-dioxide [ No CAS ]
  • 13
  • [ 59804-37-4 ]
  • N-(2-chlorophenyl)-4-hydroxy-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide [ No CAS ]
  • 14
  • [ 59804-37-4 ]
  • [ 868393-67-3 ]
  • 15
  • [ 59804-37-4 ]
  • 4-hydroxy-N-(4-methoxyphenyl)-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide [ No CAS ]
  • 16
  • [ 59804-37-4 ]
  • 4-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide [ No CAS ]
  • 17
  • [ 59804-37-4 ]
  • 4-hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide [ No CAS ]
  • 18
  • [ 59804-37-4 ]
  • [ 59804-36-3 ]
  • 19
  • [ 59804-37-4 ]
  • [ 59804-41-0 ]
  • 20
  • [ 59804-37-4 ]
  • [ 59804-42-1 ]
  • 21
  • [ 59804-37-4 ]
  • [ 98827-42-0 ]
  • 22
  • [ 59804-37-4 ]
  • 4-hydroxy-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide [ No CAS ]
  • 26
  • [ 98827-44-2 ]
  • [ 59804-37-4 ]
 

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