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Chemical Structure| 555-43-1 Chemical Structure| 555-43-1
Chemical Structure| 555-43-1

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CAS No.: 555-43-1

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Tristearin is a saturated triglyceride playing a crucial role in lipid metabolism. It influences energy balance and adipose tissue function through fatty acid metabolism signaling pathways such as PPAR-γ and AMPK, with potential value in obesity and metabolic syndrome research.

Synonyms: Glycerol tristearate; 1,2,3-Tristearoyl Glycerol; Trioctadecanoin

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Kadela, Karolina ; Tott, Szymon ; Kosowska, Karolina ; Wrobel, Tomasz ;

Abstract: The photothermal expansion in photothermal infrared microspectroscopy has traditionally been studied at room temperature. To enable measurements in a different temperature range, a temperature-controlled stage was fitted into the O-PTIR microscope to evaluate the O-PTIR signal of tristearin and polymers during temperature reduction from room temperature down to -100 °C. Therefore, we report the first successful temperature-controlled spectroscopic measurements and imaging of samples using O-PTIR in co-propagating mode. Moreover, for the first time we observed an up to 3- times increase in O-PTIR signal with decreasing temperature, with a maximum at -20 °C .

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Kadela, Karolina ; Tott, Szymon ; Kosowska, Karolina ; Stepanenko, Tetiana ; Roman, Maciej ; Wrobel, Tomasz

Abstract: Optical photothermal infrared (O-PTIR) microspectroscopy is an emerging label-free IR super resolution technique with a growing base of applicationsin soft materials. The photothermal effect has traditionally been studied at room temperature, but apart from expanding the scope of samples, there was an open question whether the signal itself would benefit from a lower temperature, as the photoinduced heating could be more localized, thus increasing the signal. To enable such measurements, a temperature-controlled stage was fitted into the O-PTIR microscope to evaluate the O-PTIR signal of tristearin and polymers during temperature lowering from room temperature down to -100 °C. Therefore, we report the first successful temperature-controlled spectroscopic measurements and imaging of samples at subzero temperatures using O-PTIR. Moreover, for the first time, we observed an up to 3 times increase in O-PTIR signal with decreasing temperature, with a maximum at -20 °C. This also propagates to an increase in the limit of detection of a thin protein film sample from a thickness of ca. 400 nm to ca. 300 nm.

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Product Details of Tristearin

CAS No. :555-43-1
Formula : C57H110O6
M.W : 891.48
SMILES Code : CCCCCCCCCCCCCCCCCC(OCC(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
Synonyms :
Glycerol tristearate; 1,2,3-Tristearoyl Glycerol; Trioctadecanoin
MDL No. :MFCD00036230
InChI Key :DCXXMTOCNZCJGO-UHFFFAOYSA-N
Pubchem ID :11146

Safety of Tristearin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338
 

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