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Chemical Structure| 548-73-2 Chemical Structure| 548-73-2

Structure of Droperidol
CAS No.: 548-73-2

Chemical Structure| 548-73-2

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CAS No.: 548-73-2

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Droperidol is an antagonist of dopamine-2 receptor.

Synonyms: Dehydrobenzperidol; DHBP; Taylor Brand of Droperidol

4.5 *For Research Use Only !

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Product Details of Droperidol

CAS No. :548-73-2
Formula : C22H22FN3O2
M.W : 379.43
SMILES Code : O=C1NC2=CC=CC=C2N1C3=CCN(CCCC(C4=CC=C(F)C=C4)=O)CC3
Synonyms :
Dehydrobenzperidol; DHBP; Taylor Brand of Droperidol
MDL No. :MFCD00083290

Safety of Droperidol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P301+P312+P330

Related Pathways of Droperidol

GPCR

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03506789 Postoperative Pain Phase 4 Recruiting June 30, 2020 Denmark ... More >> Gildh?j Privathospital Not yet recruiting Br?ndbyvester, Denmark, 2605 Contact: Niels A Pedersen, MD ?? ?? ?? Bispebjerg Hospital Recruiting Copenhagen, Denmark, 2400 Contact: Troels H Lunn, DMSc ?? ?? ?? Sj?llands Universitetshospital, K?ge Not yet recruiting K?ge, Denmark, 4600 Contact: Ole Mathiesen, MD, PhD, Assoc Prof. ?? ?? ?? N?stsved Sygehus Recruiting N?stved, Denmark, 4700 Contact: Kasper S Gasbjerg, MD ?? ?? ?? Odense Universitetshospital Not yet recruiting Odense, Denmark, 5000 Contact: S?ren Overgaard, DMSc Less <<
NCT03618082 Immediate Severe Postoperative... More >> Pain Perioperative Hemodynamic Less << Phase 3 Not yet recruiting March 31, 2021 France ... More >> CHU Clermont-Ferrand Not yet recruiting Clermont-Ferrand, Auvergne, France, 63003 Contact: Lise LACLAUTRE ?? 04 73 75 49 63 ?? drci@chu-clermontferrand.fr ?? Principal Investigator: Jean-Etienne BAZIN ?? ?? ?? Sub-Investigator: Bernard ALLAOUICHE ?? ?? ?? Sub-Investigator: Emmanuel FUTIER ?? ?? ?? Sub-Investigator: Lionel BOUVET ?? ?? ?? Sub-Investigator: Régis FUZIER ?? ?? ?? Sub-Investigator: Elizabeth GAERTNER ?? ?? ?? Sub-Investigator: Mathieu JEANNE ?? ?? ?? Sub-Investigator: Hervé MUSELLEC Less <<
NCT03036514 Pain, Postoperative Not Applicable Active, not recruiting February 2019 Belgium ... More >> University hospital Antwerp Edegem, Antwerp, Belgium, 2650 Less <<
NCT03064165 Obturator Nerve Block ... More >> Total Hip Replacement Less << Phase 4 Completed - Denmark ... More >> Elective Surgery Centre Silkeborg, Denmark, DK-8600 Less <<
NCT02625181 Postoperative Nausea and Vomit... More >>ing Less << Not Applicable Completed - United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Less <<
NCT01194089 Pain, Postoperative Phase 4 Completed - United States, Minnesota ... More >> Mayo Clinic in Rochester Rochester, Minnesota, United States, 55905 Less <<
NCT02600741 - Completed - -
NCT01194089 - Completed - -
NCT01470846 Extended Ileal Resection Under... More >> Laparotomy Total Proctocolectomy Under Laparotomy Colectomy Left/Right/Total Under Laparotomy Rectosigmoidal Resection Under Laparotomy Anterior Resection of Rectum Under Laparotomy Abdomino-perineal Amputation Under Laparotomy Less << Phase 4 Terminated(Lack of patients el... More >>igible for the study) Less << - France ... More >> CHU de Limoges - Service d'anesthésie-réanimation Limoges, France, 87042 Less <<
NCT01594749 Chemotherapy-Induced Nausea an... More >>d Vomiting (CINV) Less << Phase 3 Completed - -
NCT01594749 - Completed - -
NCT00209885 Cholecystolithiasis Phase 4 Unknown - Denmark ... More >> Dept of Anaesthesia, Hvidovre Hospital Not yet recruiting Copenhagen, Hvidovre, Denmark, 2650 Contact: Kenneth Jensen, M.D. ?? +45 36 32 62 90 ?? kenneth.jensen@hh.hosp.dk ?? Principal Investigator: Kenneth Jensen, M.D. Less <<
NCT01592708 Post-operative Nausea ... More >> Post-operative Vomiting Nausea Persistent Less << Not Applicable Completed - United States, North Carolina ... More >> UNC-Chapel Hill Chapel Hill, North Carolina, United States, 27514 Less <<
NCT01303809 Morbid Obesity Not Applicable Completed - New Zealand ... More >> Manukau Surgery Centre Auckland, New Zealand, 2025 Less <<
NCT02078336 Dental Care for Disabled Phase 4 Unknown August 2014 Belgium ... More >> Katholieke Universiteit Leuven Recruiting Leuven, Belgium, 3000 Contact: Dominique Declerck ?? ?? dominique.declerck@med.kuleuven.be ?? Contact: Ine Opsomer ?? ?? ine.opsomer@uzleuven.be Less <<
NCT01592708 - Completed - -
NCT01765829 Psychosis Nos/Other Phase 3 Unknown November 2015 Spain ... More >> Mental Health Unit Villamartín Recruiting Villamartín, Cádiz, Spain, 11650 Contact: José María Mongil San Juan, MD ?? 0034956040209 ?? cheman45@gmail.com ?? Principal Investigator: José María Mongil San Juan, MD ?? ?? ?? Mental Health Unit Baza Recruiting Baza, Granada, Spain, 18800 Contact: Eva Bravo Barba, MD ?? ?? eva.bravo.barba@gmail.com ?? Principal Investigator: Eva Bravo Barba, MD ?? ?? ?? Mental Health Unit Motril Recruiting Motril, Granada, Spain, 18600 Contact: María Luisa Barrigón Estévez, MD ?? 0034958038849 ?? marial.barrigon.sspa@juntadeandalucia.es ?? Principal Investigator: María Luisa Barrigón Estévez, MD ?? ?? ?? Mental Health Unit Andújar Recruiting Andújar, Jaén, Spain, 23740 Contact: Fernando Sarramea Crespo, MD, PhD ?? 0034953021717 ?? fernandosarramea@hotmail.com ?? Principal Investigator: Farnando Sarramea Crespo, MD, PhD ?? ?? ?? Mental Health Unit Martos Recruiting Martos, Jaén, Spain, 23600 Contact: Miguel Ortigosa Luque, MD ?? ?? migueortigosa@hotmail.com ?? Principal Investigator: Miguel Ortigosa Luque, MD ?? ?? ?? Mental Health Unit Miraflores Not yet recruiting Alcobendas, Madrid, Spain, 28100 Contact: María Luisa Zamarro Arraz, MD, PhD ?? 0034916530108 ?? zamarroluisa@yahoo.es ?? Principal Investigator: María Luisa Zamarro Arraz, MD, PhD ?? ?? ?? Hospital Infanta Sofía Not yet recruiting San Sebastian de los Reyes, Madrid, Spain, 28702 Contact: María Rosario Gutiérrez Labrador, MD ?? ?? rosagutierrez@psiquiatra.e.telefonica.net ?? Principal Investigator: María Rosario Guitiérrez Labrador, MD ?? ?? ?? Mental Health Unit Valle del Guadalhorce Not yet recruiting Cártama, Málaga, Spain, 29580 Contact: Daniel Gutiérrez Castillo, MD ?? 0034951033931 ?? dgutierrezcastillo@gmail.com ?? Principal Investigator: Daniel Gutiérrez Castillo, MD ?? ?? ?? Mental Health Unit Las Lagunas Not yet recruiting Fuengiróla, Málaga, Spain, 29650 Contact: María Isabel Osuna Carmona, MD ?? ?? maribelosunac@hotmail.com ?? Principal Investigator: María Isabel Osuna Carmona, MD ?? ?? ?? Fundación Argibide Not yet recruiting Pamplona, Navarra, Spain, 31007 Contact: Ignacio Mata Pastor, MD, PhD ?? 0034948266650 ?? nacho.mata70@gmail.com ?? Principal Investigator: Ignacio Mata Pastor, MD, PhD ?? ?? ?? Hospital El Tomillar Recruiting Dos Hermanas, Seville, Spain, 41700 Contact: Joaquín Carlos Martín Mu?oz, MD, PhD ?? 0034955016083 ?? joaquinmartin@hotmail.com ?? Principal Investigator: Joaquín Carlos Martín Mu?oz, MD, PhD ?? ?? ?? Hospital Francesc de Borja Recruiting Gandía, Valencia, Spain, 46700 Contact: María Lacruz Silvestre, MD, PhD ?? ?? maria.lacruz.silvestre@gmail.com ?? Principal Investigator: María Lacruz Silvestre, MD, PhD ?? ?? ?? Hospital de Basurto Not yet recruiting Bilbao, Spain, 48013 Contact: Sonia Bustamante Madariaga, MD, Phd ?? 0034944 006137 ?? sonia.bustamantemadariaga@osakidetza.net ?? Principal Investigator: Sonia Bustamante Madariaga, MD, PhD ?? ?? ?? Mental Health Unit Tetuán Not yet recruiting Madrid, Spain, 28003 Contact: Mariano Hernández Monsalve, MD, PhD ?? 0034915347363 ?? hergoico@gmail.com ?? Contact: Ruth Berdún Pe, MD ?? ?? ruthberdun@yahoo.es ?? Principal Investigator: Mariano Hernández Monsalve, MD, PhD ?? ?? ?? Lafora Hospital Not yet recruiting Madrid, Spain, 28049 Contact: Juan Dios Molina Martín, MD, PhD ?? ?? jmolinamar@hotmail.com ?? Principal Investigator: Juan Dios Molina Martín, MD, PhD ?? ?? ?? Hospital Carlos Haya Recruiting Málaga, Spain, 29009 Contact: Fermín Mayoral Cleríes, Md, PhD ?? ?? fermin.mayoral.sspa@juntadeandalucia.es ?? Principal Investigator: Fermín Mayoral Cleríes, MD, PhD ?? ?? ?? Virgen del Rocío Hospital Recruiting Seville, Spain, 41013 Contact: Clara M. Rosso Fernández, MD ?? 0034955013414 ?? claram.rosso.sspa@juntadeandalucia.es ?? Contact: Miguel Ruiz Veguilla, MD, PhD ?? 0034955013414 ?? mruizveguilla@yahoo.com ?? Principal Investigator: Miguel Ruiz Veguilla, MD, PhD Less <<
NCT03023462 Inguinal Hernia ... More >> Pain, Postoperative Less << Phase 4 Recruiting June 2019 Norway ... More >> Ostfold Hospital Trust, Moss Recruiting Moss, Ostfold, Norway, 1500 Contact: Jan Sverre Vamnes, MD, Ph.D. ?? +47 91608896 ?? janvam@so-hf.no ?? Contact: Knut Inge Solbakk, md ?? +47 90933106 ?? knisol@so-hf.no Less <<
NCT02282956 Hallux Valgus Phase 4 Unknown March 2017 Switzerland ... More >> Spital Grabs Recruiting Grabs, Switzerland, 9472 Contact: Sabine Schoenfeld, MD ?? 0041817725662 ?? sabine.schoenfeld@srrws.ch ?? Contact: Volha Berning, MD ?? 0041817725654 ?? volha.berning@srrws.ch Less <<
NCT03277391 Regional Anesthesia ... More >> Thoracic Surgery Post-operative Pain Post-operative Chronic Pain Pharmacokinetic Analysis Serratus Anterior Plane Block Less << Not Applicable Recruiting May 2018 Belgium ... More >> Hopital Erasme Recruiting Anderlecht, Bruxelles, Belgium, 1070 Contact ?? +3225553111 Less <<
NCT02744495 Postoperative Vomiting ... More >> Postoperative Nausea Postoperative Emesis Less << Phase 3 Completed - France ... More >> Parly2 Le Chesnay, France, 78150 Less <<
NCT01434017 Postoperative Nausea and Vomit... More >>ing Less << Phase 4 Completed - Switzerland ... More >> Centre Hospitalier Universitaire Vaudois and University of Lausanne Lausanne, Vaud, Switzerland, 1011 Less <<
NCT01432977 Pain Phase 3 Completed - France ... More >> Chirurgie Ped Limoges, France, 87042 Service Anesthésie Limoges, France, 87042 Less <<
NCT01739985 Postoperative Vomiting Not Applicable Completed - France ... More >> Necker Hospital Paris, France, 75015 Less <<
NCT01942343 Akathisia Phase 3 Completed - France ... More >> Les H?pitaux Universitaires de Strasbourg Strasbourg, Alsace, France, 67000 Less <<
NCT01679093 Interaction Between Antiemetic... More >> Drugs and Paracetamol Less << Phase 3 Completed - France ... More >> H?pital Claude Huriez, CHRU Lille, France, 59000 Less <<
NCT01819857 Cardiac Repolarization Phase 4 Completed - Poland ... More >> Medical University of Gdansk Gdansk, Poland, 80-214 Less <<
NCT00445055 Nausea|Vomiting PHASE4 TERMINATED 2025-04-09 Département d'Anesthésie-Réani... More >>mation II ; Groupe Hospitalier Sud, CHU de Bordeaux, PESSAC Cedex, 33604, France Less <<
NCT00624208 Myocardial Repolarization Not Applicable Completed - Canada, British Columbia ... More >> BC Children's Hospital Vancouver, British Columbia, Canada, V6H 3V4 Less <<
NCT01406860 Primary Headaches (Includes Mi... More >>graines, Tension, Cluster Headaches) Less << Not Applicable Terminated(lack of enrollment/... More >>drug shortages) Less << - United States, Iowa ... More >> University of Iowa Hospitals and Clinics Iowa City, Iowa, United States, 52242 Less <<
NCT01406860 - Terminated(lack of enrollment/... More >>drug shortages) Less << - -
NCT00702442 Vomiting Phase 4 Completed - Greece ... More >> 3rd Department of Surgery, AHEPA University Hospital Thessaloniki, Macedonia, Greece, 55236 3rd Department of Surgery, AHEPA University Hospital Thessaloniki, Greece, 55236 Less <<
NCT03546088 Airway Management Not Applicable Completed - Romania ... More >> Cluj County Emergency Hospital- ENT Clinic Cluj Napoca, Cluj, Romania, 400006 Less <<
NCT03677323 Hallux Valgus ... More >> Surgery Less << Not Applicable Not yet recruiting December 31, 2018 France ... More >> Clinique Saint Jean Not yet recruiting Montpellier, France, 34090 Contact: Julie SOULIER ?? + 33 4 67 61 21 52 ?? julie.soulier@capsante.fr ?? Principal Investigator: Thomas PILLANT, MD ?? ?? ?? Sub-Investigator: Aurélien BONNAL, MD Less <<
NCT04411069 Postoperative Nausea|Postopera... More >>tive Vomiting Less << PHASE2 COMPLETED 2021-03-20 Cancer Institute of the State ... More >>of Sao Paulo - ICESP, Sao Paulo, S?o Paulo, 01403010, Brazil Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.64mL

0.53mL

0.26mL

13.18mL

2.64mL

1.32mL

26.36mL

5.27mL

2.64mL
Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

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