成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 52462-29-0 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 52462-29-0
Chemical Structure| 52462-29-0
Structure of 52462-29-0 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 52462-29-0 ]

Related Doc. of [ 52462-29-0 ]

Alternatived Products of [ 52462-29-0 ]
Product Citations

Product Details of [ 52462-29-0 ]

CAS No. :52462-29-0 MDL No. :MFCD00064793
Formula : C20H28Cl4Ru2 Boiling Point : -
Linear Structure Formula :[Ru2Cl4((CH3)2CHC6H4CH3)2] InChI Key :LAXRNWSASWOFOT-UHFFFAOYSA-J
M.W : 612.39 Pubchem ID :10908223
Synonyms :

Calculated chemistry of [ 52462-29-0 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 26
Num. arom. heavy atoms : 0
Fraction Csp3 : 0.4
Num. rotatable bonds : 2
Num. H-bond acceptors : 0.0
Num. H-bond donors : 0.0
Molar Refractivity : 104.97
TPSA : 0.0 ?2

Pharmacokinetics

GI absorption : Low
BBB permeant : No
P-gp substrate : Yes
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : Yes
Log Kp (skin permeation) : -6.26 cm/s

Lipophilicity

Log Po/w (iLOGP) : 0.0
Log Po/w (XLOGP3) : 5.25
Log Po/w (WLOGP) : -6.8
Log Po/w (MLOGP) : 6.33
Log Po/w (SILICOS-IT) : 6.34
Consensus Log Po/w : 2.23

Druglikeness

Lipinski : 2.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 4.0
Bioavailability Score : 0.17

Water Solubility

Log S (ESOL) : -6.76
Solubility : 0.000104 mg/ml ; 0.000000173 mol/l
Class : Poorly soluble
Log S (Ali) : -5.0
Solubility : 0.00606 mg/ml ; 0.00001 mol/l
Class : Moderately soluble
Log S (SILICOS-IT) : -8.3
Solubility : 0.00000301 mg/ml ; 0.000000005 mol/l
Class : Poorly soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 2.0
Synthetic accessibility : 4.85

Safety of [ 52462-29-0 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P273-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H412 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 52462-29-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 52462-29-0 ]

[ 52462-29-0 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 52462-29-0 ]
  • [ 22795-99-9 ]
  • [Ru(II)((S)-(-)-2-aminomethyl-1-ethylpyrrolidine)(η6-p-cymene)Cl]Cl [ No CAS ]
  • 2
  • [ 52462-29-0 ]
  • [ 13406-29-6 ]
  • [ 169829-74-7 ]
YieldReaction ConditionsOperation in experiment
72% In tetrahydrofuran; at 20℃; for 2h;Inert atmosphere; General procedure: A 50-mL round-bottom flask was charged with [Ru(p-cymene)Cl2]2 (0.2029 g, 0.331 mmol) and CH2Cl2(20 mL). To the orange solution was added P(C6H4F)3 (0.2199 g, 0.695 mmol), and the mixture was leftto stir for 3 h at room temperature. The volatiles were removed in vacuo to leave a dark red oil, andhexanes were added to precipitate a solid product. The resulting orange solid was collected by vacuumfiltration and dried in vacuo (0.3529 g, 86percent yield).
  • 3
  • [ 6624-49-3 ]
  • [ 52462-29-0 ]
  • C20H20ClNO2Ru [ No CAS ]
YieldReaction ConditionsOperation in experiment
61.8% In ethanol; at 20℃; for 2h; To a warm solution of [Ru(eta6-p-cymene)Cl2]2 (61 mg, 0.1 mmol) in ethanol (5 ml) <strong>[6624-49-3]isoquinoline-3-carboxylic acid</strong> (HL7) (38 mg,0.2 mmol) in ethanol (3 ml) was added. The mixture was stirred at room temperature for 2 h. The yellow product was filtered off, washed with EtOH (5 ml) and dried in air.
  • 4
  • [ 55589-47-4 ]
  • [ 52462-29-0 ]
  • [ 62-53-3 ]
  • C23H26ClN2Ru(1+)*Cl(1-) [ No CAS ]
  • 5
  • [ 55589-47-4 ]
  • [ 52462-29-0 ]
  • [ 98-16-8 ]
  • C24H25ClF3N2Ru(1+)*Cl(1-) [ No CAS ]
  • 6
  • [ 55589-47-4 ]
  • [ 52462-29-0 ]
  • [ 108-42-9 ]
  • C23H25Cl2N2Ru(1+)*Cl(1-) [ No CAS ]
  • 7
  • [ 55589-47-4 ]
  • [ 52462-29-0 ]
  • [ 134-32-7 ]
  • C27H28ClN2Ru(1+)*Cl(1-) [ No CAS ]
  • 8
  • [ 55589-47-4 ]
  • [ 83-55-6 ]
  • [ 52462-29-0 ]
  • C27H28ClN2ORu(1+)*Cl(1-) [ No CAS ]
  • 9
  • [ 55589-47-4 ]
  • [ 52462-29-0 ]
  • [ 104-94-9 ]
  • C24H28ClN2ORu(1+)*Cl(1-) [ No CAS ]
  • 10
  • [ 52462-29-0 ]
  • [ 2622-63-1 ]
  • chloro(η6-p-cymene)(1-methyl-2-phenyl-1H-benzo[d]imidazole-κC,N)ruthenium(II), [ No CAS ]
YieldReaction ConditionsOperation in experiment
60% With potassium acetate; In dichloromethane; at 20℃; for 20h;Inert atmosphere; Schlenk technique; Dichloromethane (10 mL) was added to dichloro(pcymene)ruthenium(II) dimer (0.16 mmol) in a round bottom flask. To this solution were added, L6 (0.33 mmol) followed by potassium acetate(0.38 mmol). The reaction mixturewas stirred at room temperature for 20 h. Then the solvent was evaporated and the residue leftbehind was dissolved in dichloromethane and the mixture wasfiltered. The filtratewas then added to large volume of diethyl etherresulting in a precipitate which was filtered and washed withdiethyl ether and dried. (90 mg, 60percent yield) 1H NMR (CDCl3,400 MHz): delta 0.80 (3H, d, J 6.8 Hz, isopropyl), 0.94 (3H, d,J 6.8 Hz, isopropyl), 2.08 (3H, s, methyl), 2.31 (1H, m, isopropyl),4.10 (3H, s, N-methyl), 5.14 (1H, d, J 5.9 Hz, cymene), 5.36 (1H, d,J 5.9 Hz cymene), 5.70 (1H, d, J 5.9 Hz, cymene), 5.84 (1H, d,J 5.9 Hz, cymene) 7.07 (1H, m, ArH), 7.21 (1H, m, ArH), 7.40 (3H, m,ArH), 7.80 (1H, m, ArH), 7.9 (1H, d, J 7.6 Hz, ArH), 8.33 (1H, d,J 7.6 Hz, ArH). 13C NMR (CDCl3, 100 MHz): delta 19.42, 22.36, 23.08,31.35, 32.41, 81.77, 82.17, 89.26, 89.77, 99.43, 101.55, 110.27, 117.49,122.89, 123.48, 123.61, 124.80,129.36, 134.62, 136.74, 140.99, 141.84,158.86, 183.66. Elemental analysis for C24H25Cl1N2Ru, calcd. (percent) C,60.31; H, 5.27; N, 5.86. Found: C, 60.16; H, 5.14; N, 5.90.
Recommend Products
Same Skeleton Products
Historical Records
; ;