成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 51773-92-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 51773-92-3
Chemical Structure| 51773-92-3
Structure of 51773-92-3 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 51773-92-3 ]

Related Doc. of [ 51773-92-3 ]

Alternatived Products of [ 51773-92-3 ]
Product Citations

Product Details of [ 51773-92-3 ]

CAS No. :51773-92-3 MDL No. :MFCD00797519
Formula : C17H17ClF6N2O Boiling Point : No data available
Linear Structure Formula :- InChI Key :-
M.W : 414.77 Pubchem ID :-
Synonyms :
Mefloquin HCl
Chemical Name :rel-(S)-(2,8-Bis(trifluoromethyl)quinolin-4-yl)((R)-piperidin-2-yl)methanol hydrochloride

Calculated chemistry of [ 51773-92-3 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 27
Num. arom. heavy atoms : 10
Fraction Csp3 : 0.47
Num. rotatable bonds : 4
Num. H-bond acceptors : 9.0
Num. H-bond donors : 2.0
Molar Refractivity : 93.48
TPSA : 45.15 ?2

Pharmacokinetics

GI absorption : Low
BBB permeant : No
P-gp substrate : Yes
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : Yes
CYP3A4 inhibitor : Yes
Log Kp (skin permeation) : -5.68 cm/s

Lipophilicity

Log Po/w (iLOGP) : 0.0
Log Po/w (XLOGP3) : 4.43
Log Po/w (WLOGP) : 6.85
Log Po/w (MLOGP) : 3.65
Log Po/w (SILICOS-IT) : 4.8
Consensus Log Po/w : 3.95

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 1.0
Muegge : 0.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -5.21
Solubility : 0.00254 mg/ml ; 0.00000613 mol/l
Class : Moderately soluble
Log S (Ali) : -5.1
Solubility : 0.00332 mg/ml ; 0.00000801 mol/l
Class : Moderately soluble
Log S (SILICOS-IT) : -6.1
Solubility : 0.000333 mg/ml ; 0.000000802 mol/l
Class : Poorly soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 2.0
Synthetic accessibility : 3.33

Safety of [ 51773-92-3 ]

Signal Word:Warning Class:
Precautionary Statements:P280-P305+P351+P338 UN#:
Hazard Statements:H302 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 51773-92-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 51773-92-3 ]
Recommend Products
Same Skeleton Products
Historical Records
; ;