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[ CAS No. 498-60-2 ] {[proInfo.proName]}

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Chemical Structure| 498-60-2
Chemical Structure| 498-60-2
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Product Details of [ 498-60-2 ]

CAS No. :498-60-2 MDL No. :MFCD00010424
Formula : C5H4O2 Boiling Point : -
Linear Structure Formula :- InChI Key :AZVSIHIBYRHSLB-UHFFFAOYSA-N
M.W : 96.08 Pubchem ID :10351
Synonyms :
Chemical Name :Furan-3-carbaldehyde

Safety of [ 498-60-2 ]

Signal Word:Danger Class:3
Precautionary Statements:P261-P305+P351+P338 UN#:1989
Hazard Statements:H225-H315-H319-H335 Packing Group:Ⅲ
GHS Pictogram:

Application In Synthesis of [ 498-60-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 498-60-2 ]

[ 498-60-2 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 498-60-2 ]
  • [ 347174-05-4 ]
  • [ 871930-30-2 ]
  • 2
  • [ 498-60-2 ]
  • [ 13214-64-7 ]
  • 4-[furan-3-ylmethylene]-2-(4-methoxy-phenyl)-(4H)-oxazol-5-one [ No CAS ]
  • 3
  • [ 498-60-2 ]
  • [ 2478-38-8 ]
  • C15H14O5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium hydroxide; In ethanol; water; for 4h; General procedure: A suspension of aromatic aldehyde 1 (40 mmol) and aromaticketone 2 (40 mmol) in mixture of 10 ml saturatedNaOH solution in water and 10 ml ethanol was stirred for 4 hat 20 C to obtain pure chalcone 3 (Ozdemir et al. 2007;Chimenti et al. 2010). Further, mixture of chalcone 3 (10mmol) and thiosemicarbazide (20 mmol) was refluxed understirring with KOH (20 mmol) in 70mL EtOH for approximately6 h to get N-thiocarbamoyl pyrazole derivative 4(Scheme 1). This N-thiocarbamoyl pyrazole derivative 4 (10mmol) was added in appropriate quantity of EtOAc and wasrefluxed with ethyl bromoacetate (30 mmol) for 1.5 h (EISabbaghet al. 2009; Seebacher et al. 2003). After completionof reaction, the reaction mixture was mixed with CHCl3and allowed to evaporate to obtain pyrazol-1-yl-1,3-thaizol-4(5H)-one derivative (5a-5m, Fig. 2). The refined compoundwas obtained by subsequent purification withrecrystallization by using ethanol-acetone (1:1).
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Related Functional Groups of
[ 498-60-2 ]

Aldehydes

Chemical Structure| 885465-98-5

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4-(Furan-3-yl)benzaldehyde

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Related Parent Nucleus of
[ 498-60-2 ]

Furans

Chemical Structure| 885465-98-5

[ 885465-98-5 ]

4-(Furan-3-yl)benzaldehyde

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