成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 478-43-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 478-43-3
Chemical Structure| 478-43-3
Structure of 478-43-3 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 478-43-3 ]

Related Doc. of [ 478-43-3 ]

Alternatived Products of [ 478-43-3 ]
Product Citations

Product Citations

Twitty, Alyssa ; Barnes, Hamlin ; Levy, Noa , et al. DOI: PubMed ID:

Abstract: The natural anthraquinone rhein has been identified as a novel herbicide with a potentially new mode of action using a generative AI system for functional molecules discovery. Its herbicidal activity was light-dependent and resulted in rapid burndown symptoms on leaves of treated plants. Rhein interferes with photosynthesis by acting as an electron diverter at the level of photosystem I (PSI). The redox potential of rhein suggests that it accepts electrons between P700 and NADP+ of PSI. This is consistent with the redox potential of rhein that enables it to accept electrons from flavoproteins. Ferredoxin-NAPD+ reductase is a flavoprotein with a redox potential near that of rhein. Thus, it is currently hypothesized that rhein acts as an electron acceptor at or near the PSI Ferredoxin-NAPD+ reductase to form a radical and generate reactive oxygen species that drive the light-dependent herbicidal effect which is observed in treated plants from greenhouse trials.

Keywords: AI ; Artificial intelligence ; Generative AI ; Mode of action ; Photosystem I ; Anthraquinone ; Natural product ; Light-dependent ; Electron acceptor ; ROS ; Flavoprotein

Purchased from AmBeed:

Product Details of [ 478-43-3 ]

CAS No. :478-43-3 MDL No. :MFCD00009618
Formula : C15H8O6 Boiling Point : -
Linear Structure Formula :- InChI Key :FCDLCPWAQCPTKC-UHFFFAOYSA-N
M.W : 284.22 Pubchem ID :10168
Synonyms :
Rheic Acid;Rhubarb yellow;Rheic acid, Cassic acid;Rheinic Acid;NSC 38629;Monorhein
Chemical Name :4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

Calculated chemistry of [ 478-43-3 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 21
Num. arom. heavy atoms : 12
Fraction Csp3 : 0.0
Num. rotatable bonds : 1
Num. H-bond acceptors : 6.0
Num. H-bond donors : 3.0
Molar Refractivity : 70.75
TPSA : 111.9 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : No
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : Yes
Log Kp (skin permeation) : -6.45 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.37
Log Po/w (XLOGP3) : 2.23
Log Po/w (WLOGP) : 1.57
Log Po/w (MLOGP) : 0.29
Log Po/w (SILICOS-IT) : 1.96
Consensus Log Po/w : 1.48

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.56

Water Solubility

Log S (ESOL) : -3.36
Solubility : 0.123 mg/ml ; 0.000433 mol/l
Class : Soluble
Log S (Ali) : -4.22
Solubility : 0.0173 mg/ml ; 0.0000609 mol/l
Class : Moderately soluble
Log S (SILICOS-IT) : -3.46
Solubility : 0.0979 mg/ml ; 0.000344 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 1.0 alert
Brenk : 0.0 alert
Leadlikeness : 0.0
Synthetic accessibility : 2.58

Safety of [ 478-43-3 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 478-43-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 478-43-3 ]

[ 478-43-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 478-43-3 ]
  • [ 29390-67-8 ]
  • mono(6-rhein-amino-6-deoxy)-β-cyclodextrin [ No CAS ]
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Similar Product of
[ 478-43-3 ]

Chemical Structure| 1189928-10-6

A1230160[ 1189928-10-6 ]

Rhein-13C4

Reason: Stable Isotope

; ;