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Chemical Structure| 4597-87-9 Chemical Structure| 4597-87-9

Structure of 2-(Methylamino)pyridine
CAS No.: 4597-87-9

Chemical Structure| 4597-87-9

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Product Details of [ 4597-87-9 ]

CAS No. :4597-87-9
Formula : C6H8N2
M.W : 108.14
SMILES Code : CNC1=NC=CC=C1
MDL No. :MFCD00006250
InChI Key :SVEUVITYHIHZQE-UHFFFAOYSA-N
Pubchem ID :20727

Safety of [ 4597-87-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302+H312+H332-H315-H319-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 4597-87-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4597-87-9 ]

[ 4597-87-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4597-87-9 ]
  • [ 105806-13-1 ]
  • [ 1152110-51-4 ]
YieldReaction ConditionsOperation in experiment
90% With triethylamine; In tetrahydrofuran; for 4h; Part A: 6-Chloro-5-fluoro-2-methyl-N-(2-pyridinylmethyl)-4-pyrimidinamine. 4,6-Dichloro-5-fluoro-2-methylpyrimidine (0.2 g, 1.1 11 mmol) was dissolved in THF (1 ml_). To this solution was added triethylamine (0.17 ml_, 1.22 mmol), followed by commercially available (2-pyridinylmethyl)amine (0.11 ml_, 1.067 mmol), which was dissolved in THF (1 ml_). The reaction was left to stir for 4 hours. The reaction mixture was diluted with water and extracted with ether. The organics were dried (MgSO4) and concentrated to provide 6-chloro-5-fluoro-2-methyl-N-(2-pyridinylmethyl)-4- pyrimidinamine as a yellow wax (0.2517 g, 90%). LCMS: (M+H)+ = 253.3.
 

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