成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 41153-30-4 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 41153-30-4
Chemical Structure| 41153-30-4
Structure of 41153-30-4 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 41153-30-4 ]

Related Doc. of [ 41153-30-4 ]

Alternatived Products of [ 41153-30-4 ]
Product Citations

Product Details of [ 41153-30-4 ]

CAS No. :41153-30-4 MDL No. :MFCD00079672
Formula : C14H18FNO4 Boiling Point : -
Linear Structure Formula :- InChI Key :RCXSXRAUMLKRRL-NSHDSACASA-N
M.W : 283.30 Pubchem ID :7020910
Synonyms :
(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid

Calculated chemistry of [ 41153-30-4 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 20
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.43
Num. rotatable bonds : 7
Num. H-bond acceptors : 5.0
Num. H-bond donors : 2.0
Molar Refractivity : 71.3
TPSA : 75.63 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -5.78 cm/s

Lipophilicity

Log Po/w (iLOGP) : 2.45
Log Po/w (XLOGP3) : 3.16
Log Po/w (WLOGP) : 2.77
Log Po/w (MLOGP) : 2.36
Log Po/w (SILICOS-IT) : 2.08
Consensus Log Po/w : 2.56

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 0.0
Bioavailability Score : 0.56

Water Solubility

Log S (ESOL) : -3.35
Solubility : 0.127 mg/ml ; 0.00045 mol/l
Class : Soluble
Log S (Ali) : -4.42
Solubility : 0.0108 mg/ml ; 0.0000381 mol/l
Class : Moderately soluble
Log S (SILICOS-IT) : -3.45
Solubility : 0.1 mg/ml ; 0.000354 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 0.0 alert
Leadlikeness : 0.0
Synthetic accessibility : 2.77

Safety of [ 41153-30-4 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 41153-30-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 41153-30-4 ]

[ 41153-30-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 5382-17-2 ]
  • [ 41153-30-4 ]
  • [ 186431-68-5 ]
YieldReaction ConditionsOperation in experiment
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20℃; for 16.0h; To a stirred solution OF BOC-3- (4-FLUOROPHENYL)- (S)-ALANINE (LO. OG, 35. 3MMOL), <strong>[5382-17-2]4-hydroxypiperidine hydrochloride</strong> (5. 1G, 37. 1MMOL) and HOBt (7.2g, 52. 9MMOL) in DMF (lOOmL), was added DIPEA (12. 3mL, 70. 6MMOL) and after 5MIN, EDCI (7.4g, 38. 8MMOL) and the reaction stirred at rt for 16H. The solvent was removed in vacuo and the residue partitioned between water (150ML) and ethyl acetate (2 x 150ML). The combined organic fractions were washed with sodium hydroxide solution (2M, 50ML), hydrochloric acid (2N, 50ML), dried (MGS04) and concentrated in vacuo. The product was chromatographed on silica gel eluting with ethyl acetate to give the title compound as a white solid. m/z (ES+) = 367 [M+ H] + ; RT = 3.28min.
  • 2
  • [ 41153-30-4 ]
  • [ 198904-31-3 ]
  • (5S,10S,11S,14S)-11-benzyl-5,14-di-tert-butyl-3,6,13,16-tetraoxo-8-(4-(pyridin-2-yl)benzyl)-2,17-dioxa-4,7,8,12,15-pentaazaoctadecan-10-yl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoate [ No CAS ]
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 41153-30-4 ]

Amino Acid Derivatives

Chemical Structure| 57292-45-2

[ 57292-45-2 ]

Boc-D-Phe(4-F)-OH

Similarity: 1.00

Chemical Structure| 114873-11-9

[ 114873-11-9 ]

Boc-D-Phe(3-F)-OH

Similarity: 0.99

Chemical Structure| 114873-01-7

[ 114873-01-7 ]

Boc-Phe(3-F)-OH

Similarity: 0.99

Chemical Structure| 205445-53-0

[ 205445-53-0 ]

Boc-D-3,5-Difluorophenylalanine

Similarity: 0.97

Chemical Structure| 114873-00-6

[ 114873-00-6 ]

Boc-Phe(2-F)-OH

Similarity: 0.97

; ;