成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Home Cart 0 Sign in  

[ CAS No. 3470-53-9 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 3470-53-9
Chemical Structure| 3470-53-9
Structure of 3470-53-9 * Storage: {[proInfo.prStorage]}

Please Login or Create an Account to: See VIP prices and availability

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 3470-53-9 ]

Related Doc. of [ 3470-53-9 ]

Alternatived Products of [ 3470-53-9 ]
Product Citations

Product Details of [ 3470-53-9 ]

CAS No. :3470-53-9 MDL No. :MFCD00099462
Formula : C10H11NO Boiling Point : -
Linear Structure Formula :- InChI Key :BEVVUJBVEXJGKM-UHFFFAOYSA-N
M.W : 161.20 Pubchem ID :339537
Synonyms :

Calculated chemistry of [ 3470-53-9 ]      Expand+

Physicochemical Properties

Num. heavy atoms : 12
Num. arom. heavy atoms : 6
Fraction Csp3 : 0.3
Num. rotatable bonds : 0
Num. H-bond acceptors : 1.0
Num. H-bond donors : 1.0
Molar Refractivity : 48.7
TPSA : 43.09 ?2

Pharmacokinetics

GI absorption : High
BBB permeant : Yes
P-gp substrate : No
CYP1A2 inhibitor : No
CYP2C19 inhibitor : No
CYP2C9 inhibitor : No
CYP2D6 inhibitor : No
CYP3A4 inhibitor : No
Log Kp (skin permeation) : -6.33 cm/s

Lipophilicity

Log Po/w (iLOGP) : 1.5
Log Po/w (XLOGP3) : 1.34
Log Po/w (WLOGP) : 1.8
Log Po/w (MLOGP) : 1.35
Log Po/w (SILICOS-IT) : 2.29
Consensus Log Po/w : 1.65

Druglikeness

Lipinski : 0.0
Ghose : None
Veber : 0.0
Egan : 0.0
Muegge : 1.0
Bioavailability Score : 0.55

Water Solubility

Log S (ESOL) : -2.05
Solubility : 1.42 mg/ml ; 0.00884 mol/l
Class : Soluble
Log S (Ali) : -1.85
Solubility : 2.29 mg/ml ; 0.0142 mol/l
Class : Very soluble
Log S (SILICOS-IT) : -3.02
Solubility : 0.152 mg/ml ; 0.000944 mol/l
Class : Soluble

Medicinal Chemistry

PAINS : 0.0 alert
Brenk : 1.0 alert
Leadlikeness : 1.0
Synthetic accessibility : 1.56

Safety of [ 3470-53-9 ]

Signal Word:Warning Class:
Precautionary Statements:P280-P305+P351+P338 UN#:
Hazard Statements:H317-H319 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 3470-53-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3470-53-9 ]

[ 3470-53-9 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 3470-53-9 ]
  • [ 703-67-3 ]
YieldReaction ConditionsOperation in experiment
To a solution of 6-amino-3,4-dihydronaphthalen-1(2H)-one(1.8 g, 30 mmol) in water (15 mL) and concentrated HCl (7.5 mL),sodium nitrite (2.20 g, 31.8 mmol) wasadded slowly at 0 . The mixture was stirred for another 30 min at 0 . Thentetrafluoroboric acid solution (48 wt. percent in H2O) was added dropwise.After complete reaction, the reaction mixture was filtered, washed withice-water and MeOH. The crude product was used in the next step without furtherpurification.
  • 2
  • [ 3470-53-9 ]
  • [ 51015-29-3 ]
  • 3
  • [ 20291-40-1 ]
  • [ 3470-53-9 ]
  • methyl 7-oxo-7-((5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)amino)heptanoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
89% With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20℃; To a solution of Compound la (6-Amino- 1 -tetralone) (0.50 g, 3.10 mmol), <strong>[20291-40-1]7-methoxy-7-oxoheptanoic acid</strong> (0.81 g, 4.65 mmol) and HOBt (0.21 g, 1.55 mmol) in DCM (50 mL) was added DIPEA (1.20 g, 9.31 mmol) and EDCI (0.89 g, 4.65 mmol) at 0C . After addition, the reaction mixture was slowly warmed to RT and stirred for overnight. After reaction was completed, the solvent was removed under reduced pressure. The residual was diluted with EtOAc and washed with Sat. NLLCl and Sat. NaHCCL. The combined organic layers were washed with brine and dried over MgSCL and concentrated in vacuo to afford Compound 11a (methyl7-oxo-7-((5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)amino)heptanoate) (0.88 g, 2.76 mmol, yield 89%). The product was used in next step without further purification.
Recommend Products
Same Skeleton Products

Technical Information

Historical Records

Related Functional Groups of
[ 3470-53-9 ]

Aryls

Chemical Structure| 69975-65-1

[ 69975-65-1 ]

6-Amino-2,3-dihydro-1H-inden-1-one

Similarity: 0.95

Chemical Structure| 3470-54-0

[ 3470-54-0 ]

5-Aminoindan-1-one

Similarity: 0.95

Chemical Structure| 99-03-6

[ 99-03-6 ]

1-(3-Aminophenyl)ethanone

Similarity: 0.93

Chemical Structure| 1137-41-3

[ 1137-41-3 ]

(4-Aminophenyl)(phenyl)methanone

Similarity: 0.90

Chemical Structure| 99-92-3

[ 99-92-3 ]

1-(4-Aminophenyl)ethanone

Similarity: 0.90

Ketones

Chemical Structure| 870679-59-7

[ 870679-59-7 ]

1-Amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one

Similarity: 0.95

Chemical Structure| 69975-65-1

[ 69975-65-1 ]

6-Amino-2,3-dihydro-1H-inden-1-one

Similarity: 0.95

Chemical Structure| 3470-54-0

[ 3470-54-0 ]

5-Aminoindan-1-one

Similarity: 0.95

Chemical Structure| 3470-55-1

[ 3470-55-1 ]

2-Amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one

Similarity: 0.95

Chemical Structure| 99-03-6

[ 99-03-6 ]

1-(3-Aminophenyl)ethanone

Similarity: 0.93

Amines

Chemical Structure| 870679-59-7

[ 870679-59-7 ]

1-Amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one

Similarity: 0.95

Chemical Structure| 69975-65-1

[ 69975-65-1 ]

6-Amino-2,3-dihydro-1H-inden-1-one

Similarity: 0.95

Chemical Structure| 3470-54-0

[ 3470-54-0 ]

5-Aminoindan-1-one

Similarity: 0.95

Chemical Structure| 3470-55-1

[ 3470-55-1 ]

2-Amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one

Similarity: 0.95

Chemical Structure| 99-03-6

[ 99-03-6 ]

1-(3-Aminophenyl)ethanone

Similarity: 0.93

; ;